Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: YUCEYAR
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Tytuł oryginału: The effect of perendoscopic sclerosing agent injection in Forrest's II ulcers - a pilot study from Turkey.
Autorzy: Saruc Murat, Ozden Nuri, Kucukmetin Nurten, Tuzcuoglu Isil, Yuceyar Hakan
Źródło: Med. Sci. Monitor 2002: 8 (11) s.CR735-CR739, tab., bibliogr. 21 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • gastroenterologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna
  • badanie porównawcze

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Bakcground: We aimed to clarify the outcome of perendoscopic prophylactic injection of sclerosing agent in Forrest's II ulcers. Material/Methods: Patients with upper gastrointestinal bleeding in last 6 hours were performed emergency endoscopy and were enrolled. The patients in group-1 were performed prophylactic injection therapy with 1 p.c. aethoxyclerol and then given medical treatmetn with intravenous 40 mg omeprazole twice a day and somatostatin infusion at the dose of 6 mg/day during 3 days. Group-2 patients were only given medical treatment with same agents and at same doses without having any perendoscopic therapy. Results: There were 32 pateitns in group-1 and 20 in group-2. In emergency endoscopy, 20 (62.5 p.c.) patietns had IIa ulcers and 12 (37.5 p.c.) patients had IIb ulcers in group-1. These patients underwent prophylactic perendoscopic hemostasis by 1 p.c. aethoxysclerol in addition to medical treatment. Early rebleeding occurred in 9 (28.1 p.c.) patients of group-1 and 3 (15 p.c.) in group-2 (p 0.001). At the endoscopic control after 48 hours 13 (40.6 p.c.) patients in the group-1 and 15 (75 p.c.) patients in group-2 showed improved local ulcer stigmata (p 0.001). The numbers of blood units transfused were lower in the group-2 (p = 0.002). THe hospital stay was longer in group-1 (p = 0.01). In the group-1, more endoscopic intervention was needed. Any death and the need for surgical intervention did not occurred in any groups. Conclusion: According to our resutls; the indication of perendoscopic prophylactic injection of sclreosing agent in non-bleeding ulcers with high risk of rebleeding must be reviewed by large population based, prospective, randomized trials.


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    Tytuł oryginału: Acute intermittent porphyria with acute pancreatitis and liver dysfunction.
    Autorzy: Saruc Murat, Turkel Nurten, Yuceyar Hakan, Ayhan Semin, Demir Mehmet Akif, Can Mine
    Źródło: Case Rep. Clin. Pract. Rev. 2002: 3 (4) s.234-238, il., tab., bibliogr. 8 poz.
    Sygnatura GBL: 313,612

    Hasła klasyfikacyjne GBL:
  • gastroenterologia

    Typ dokumentu:
  • praca kazuistyczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska

    Streszczenie angielskie: Background: We reported a case with acute intermittent porphyria who demonstrated acute pancreatitis and liver dysfunction. Case report: A 44-year-old white male with type II diabetes mellitus presented with colicky right upper quadrant and epigastric pain, nausea and vomiting during last two days. Two weeks prior to these complaints, he had and upper respiratory tract infection and used some drugs including terfenadine and co-trimoxazole. Physical examination revealed that he was mentally confused and he had jaundice. Abdominal examination revealed diffuse tenderness. Clinical, laboratory findings, liver histology, pancreas cytology and CT scan showed the presence of acute pancreatitis, mild liver failure and pleural effusion. His urine color was pink-purple and got darker in urine collection bag. Porphyrin studien revealed markedly elevated urine porphobilinogen, aminolevulinic acid, coproporphyrin, and uroporphyrin which suggested the diagnosis of acute intermittent porphyria. All these studies established the diagnosis of acute intermittent porphyria causing acute pancreatitis, mild hepatic failure pleural effusion and neurological signs. The patient was kept at rest and treated with total parenteral nutrition without allowing oral food intake. Large amount of glucose given by central venous route. A broad spectrum antibiotic was administered. Liver function, as well as clinical and laboratory finding of pancreatitis improved after two weeks of hospitalization. He has now been on follow-up for 6 months and he has not had any complaints. Conclusion: When a clinician...

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