Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL
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VANDENBERGHE
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Tytuł oryginału:
18 F-Fluorodeoxyglucose triple-headed coincidence detection imaging in oncology: preliminary results and comparison with dedicated PET.
Autorzy:
Winter
Frederic De,
Wiele
Christophe Van de,
Vandenberghe
Stefaan,
Vandenbossche
Bieke,
D'Asseler
Yves,
Huglo
Damien,
Dierckx
Rudi
Źródło:
Med. Sci. Monitor 2002: 8 (6) s.MT89-MT94, il., tab., bibliogr. 2 poz.
Sygnatura GBL:
313,278
Hasła klasyfikacyjne GBL:
onkologia
Typ dokumentu:
praca kliniczna
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
dorośli 45-64 r.ż.
płeć męska
płeć żeńska
Streszczenie angielskie:
Dual head coincidence (DHC) imaging has been proposed as a valuable and cheaper alternative to oncological PET. The increased sensitivity of the recently-developed triple-headed gamma camera (THC) optimized for coincidence detection has not been either validated or compared to the sensitivity of a dedicated PET system in a clinical study. Differences in contrast-to-noise-ratio (CNR) between dedicated FDG PET, DHC and THC imaging were assessed using a hot sphere phantom. Twenty-two oncological patients were prospectively studied with consecutive whole body FDG PET adn FDG THC imaging. The images were visually read by 2 experienced nuclear medicine specialists. The diagnostic sensitivity of FDG THC imaging was assessed using FDG PET as the imaging gold standard. Lesion size was determined using computed tomography or magnetic resonance imaging. The mean gain in CNR for THC as compared to DHC imaging was 35 p.c. (10 - 56 p.c.). Of 63 lesions, 58 (92 p.c.) on FDG PET were also detected wtih THC imaging. Considering only lesions smaller than 15 mm, the relative sensitivity was 86 p.c. (24.29). All lesions aboe 15 mm (n = 34) were detected using THC imaging. The first clinical results for THC imging are promising. The overall relative sensitivity in this limited series was 92 p.c. Only a few lesions smaller than 15 mm were missed.
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