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Tytuł oryginału: Papilomavirusines infekcijos paplitimas tarp ligoniu, serganciu gerklu papilomatoze, ir kai kuriu rizikos veiksniu itaka papilomavirusu persistavimui virsutiniuose kvepavimo takuose.
Tytuł angielski: Prevalence of human papillomavirus infection among patients with laryngeal papillomatosis and the influence of some risk factors on the persistence of papillomaviruses in the upper respiratory tract.
Autorzy: Velyvyte Daiva, Laiskonis Alvydas, Uloza Virgilijus, Goździcka-Józefiak Anna
Źródło: Medicina 2002: 38 (5) s.499-504, tab., bibliogr. 19 poz., sum.
Sygnatura GBL: 313,016

Hasła klasyfikacyjne GBL:
  • pulmonologia
  • onkologia
  • otorynolaryngologia

    Typ dokumentu:
  • praca kliniczna
  • praca opublikowana za granicą
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Infection with high-risk human papillomaviruses is a significant risk factor of various benign and malignant human lesions in the upper respiratory tract, skin and the genital tract. The identification of particular human papillomaviruses types is important fir identifying patients with premalignant lesions who are at risk of progression to malignancy. Our aim was to establish the prevalence of human papillomaviruses infection in the upper respiratory tract of patients with laryngeal papillomatosis, to identify viral types, to evaluate the relationship between some risk factors and persistence of human papillomviruses in the upper respiratory tract and to determine the pattern of human papilomaviruses infection. Material and methods. The gorup fo 36 patients with laryngeal papillomatosis and control group of 108 persons without any complains of respiratory system was examined. Epidemiologic characteristics and objective data were analyzed and routine laryngological examination was performed. Pharyngeal swabs of all persons and laryngeal biopsies of 17 patients were taken and analyzed for the presence fo human papillomaviruses DNA. Viral typing using the polymerase chain reaction was performed. Results. Human papillomaviruses DNA was detected in all except one case of laryngeal papillomatosis; then only 23.15 p.c. of persons without complaints of respiratory system were found human papillomaviruses positive. Human papillomaviruses 6, 11 types were predominant (in 88.9 p.c. of patients adn 19.4 p.c. of persons from control gorup). High-risk human papillomaviruses were detected in 52.78 p.c. of laryngeal papillomatosis cases and in 9.26e p.c. of control cases. Risk factors were noted statistically significantly more often in human papillomaviruses positive cases...

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