Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: TRAWIŃSKA
Liczba odnalezionych rekordów: 1



Przejście do opcji zmiany formatu | Wyświetlenie wyników w wersji do druku
1/1

Tytuł oryginału: Frequency, consequences and pharmacological treatment of gastroesophageal reflux in children with cystic fibrosis.
Autorzy: Brodzicki Jacek, Trawińska Maria, Korzon Maria
Źródło: Med. Sci. Monitor 2002: 8 (7) s.CR529-CR537, tab., bibliogr. 42 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • pediatria
  • gastroenterologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • noworodki
  • niemowlęta
  • dzieci 2-5 r.ż.
  • dzieci 6-12 r.ż.
  • dzieci 13-18 r.ż.
  • dorośli 19-44 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: Gastroesophageal reflux (GER) may aggravate chronic bronchopulmonary diseases. The study evaluated GER frequency and characteristics in children with Cysti Fibrosis (CF) as well as its consequences and pharmacological treatment. Material/Methods: 40 CF children aged 1.3 to 20 years were examined. The study methodology involved: medical files analysis, anamnesis, physical examination, growth status estimation, esophageal pH-metry and upper gastrointestinal tract endoscopy with histological examination of esophageal biopsies. Results: Based on pH-metry results, the diagnosis of GER was established in 22 children (55 p.c.). Mild GER (Index Reflux - IR 5-10 p.c.) was found in 12 children (54.5 p.c.), moderate GER (IR 10-20 p.c.) in 7 (31.8 p.c.) and severe GER (IR 20 p.c.) in 3 (13.6 p.c.). Ten patietns with moderate or severe GER underwent endoscopy, which revealed GER-related esophagitis in 8 cases. There was no statistical difference of GER frequency and degree according to: age, sex, growth status, presence of type DeltaF508 mutation in CFTR genome and typical GERD symptoms. According to the ESPGAN proposition, cisapride or cisapride with ranitidine medication was instituted. Treatment analysis was performed in 19 cases after successful follow-up examinations carried out three months later, indicating a significant decrease in reflux index, the longest episode duration and the numer of episodes longer than 5 minutes. Improvement of endoscopic picture was noticed after treatment. Conclusion: High frequency of gastroesophageal reflux and its consequences among...

    stosując format: