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Tytuł oryginału:
Annals of Diagnostic Paediatric Pathology
Tytuł angielski:
Cushing's disease in a 5 months infant due to a basophilic microadenoma of the pituitary gland.
Autorzy:
Ferraz
Maria Lucia da Fonseca,
Oliveira
Gamaniel de,
Almeida
Joao,
Reis
Marlene Antonia dos,
Teixeira
Vincente de Paula Antunes,
Castro
Eumenia Costa da Cunha
Źródło:
Ann. Diagn. Paediatr. Pathol. 2002: 6 (3/4) s.141-143, il., bibliogr. 29 poz.
Sygnatura GBL:
313,395
Hasła klasyfikacyjne GBL:
endokrynologia
onkologia
Typ dokumentu:
praca kazuistyczna
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
niemowlęta
Streszczenie angielskie:
We report a five-month old girl with classical clinical features of Cushing's syndrome. Histological findings showed a basophilic microadenoma of the pituitary gland, leading to a diagnosis of Cushing disease (CD). The child died because of untreatable septic shock. The importance of the present report resides in the age of the child at the diagnosis. CD is the most often diagnosed in children older than seven years, and our patient was only five months old when we detected the pituitary adenoma, this was the earliest case diagnosed thus far. Cushing's syndrome in pediatric patients has been rarely reported and most of the cases are due to functioning adrenal tumour, usually a malignant carcinoma but occasionally a benign adenoma. The present case shows that the pituitary of this patients should be investigated with important implications in terms of therapeutic approaches such as radiotherapy of the pituitary, which can cure the patient when treatment is started as soon as possible.
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