Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Poszukiwanie alternatywnego doustnego środka kontrastowego do obrazowania przewodu pokarmowego metodą rezonansu magnetycznego - faza badań in vitro, doniesienie wstępne.
Tytuł angielski: Searching for an alterntive oral contrast agent for Gl tract MR imaging - in vitro phase, initial report.
Autorzy: Okła Wojciech, Gołębiowski Marek, Szeszkowski Wojciech, Cieszanowski Andrzej
Źródło: Pol. J. Radiol. 2002: 67 (4) s.75-85, il., tab., bibliogr. 18 poz., sum.
Sygnatura GBL: 301,279

Hasła klasyfikacyjne GBL:
  • gastroenterologia
  • radiologia

    Typ dokumentu:
  • praca doświadczalna

    Wskaźnik treści:
  • in vitro

    Streszczenie angielskie: Background: MR has been recently considered to be suitable method for detection GT tract pathologies. A few substances (some of a natural origin) seem to act as an efficient oral MR contrast agnets. The aim of this study is to find an alternative substance, which can be administrated orally to patients in order to enhance signal intensity (SI). The ideal agent should have a biphase pattern (high SI in T1 and low in T2), and should be nontoxic and cost effective. Material/Methods: Phantom experiments were conducted with 1.5 T MR scanner. T1W and T2W sequences were used for intial estimation. Number of diffrent agents such as: water, Gd-DTPA, barium sulfate, green tea, blueberry juice, cranberry juice, blackcurrant juice, and some more were evaluated. Signal intensity was measured by using elliptical region of interest (ROI). MR imaging in one patient with stomach cancer was also performed. Results: In I1W-FFE sequence cranberry juice reached satisfactorily high signal (SI = 1760.14). In T2W - TSE sequence this substane reduced signal intensity (SI = 23.10) almost to background level. Blueberry juice appear to be the next substance capable to generate high signal (SI = 1558.31) in W1W sequence (T1-TSE). MR examination of a patient with stomach adenocarcinoma (using blueberry juice as an oral contrast agent) satisfactorily depicted and delineated tumor mass on both: T1W and T2W images.

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