Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Thrombolysis in acute myocardial infarction. Results of the Polish part of the international multicentre INJECT study.
Tytuł polski: Leczenie trombolityczne świeżego zawału serca. Porównanie skuteczności reteplazy i streptokinazy w polskiej części badania INJECT.
Autorzy: Stępińska Janina, Sadowski Zygmunt, Banaszewski Marek, Szajewski Tomasz, Wojciechowski Dariusz, Kraska Tadeusz
Źródło: Kardiol. Pol. 2002: 56 (2) s.175-187, il., tab., bibliogr. 10 poz. - Tekst równol. w jęz. pol.
Sygnatura GBL: 313,397

Hasła klasyfikacyjne GBL:
  • toksykologia
  • farmacja
  • kardiologia

    Typ dokumentu:
  • badanie porównawcze

    Wskaźnik treści:
  • ludzie
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background. The INJECT trial was an international, multicentre, double blind study designed to evaluate effectiveness and safety of reteplase versus streptokinase in the treatment of acute myocardial infarction (MI). A total of 6010 patients, including 1098 Polish citizens, were recruited between August 1993 and September 1994. Aim. To compare demographic and clinical data of the Polish subgroup with that of the INJECT population as well as to analyse reteplase and sreptokinase efficacy in the Polish subgroup. Methods. The records of the Polish patietns were compared with the data of the remaining patients recruited in the INJECT trial. Results. The Polish population differed from the other patients in respect to a significantly higher prevalence of smokers, more frequent history of hypertension or ischaemic heart disease and younger age. A 35-day mortality rate was similar in the reteplase and streptokinase groups, both in the Polish and non-Polish population. Side effects profile and mortality rate due to stroke were similar in the Polish as well as in the remaining INJECT patients. A statistically significant higher incidence of in-hospital bleeding events in the Polish group was only due to the excess in minor bleedings. In both compared groups, reteplase proved to be at least equivalent to streptokinase but with a better side effects profile and much more simple administration. Conclusions. (1) The epdiemiological differences between the Polish population and the remaining patients included in the INJECT trial imply the need for more intensive primary and secondary prevention of coronary artery disease in Polish patients...

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    Tytuł oryginału: Calcium blocker therapy before myocardial infarction increases post-infarction short - and long-term mortality. Data from the INJECT trial.
    Tytuł polski: Leczenie blokerami kanału wapniowego przed zawałem serca zwiększa ryzyko zgonu. Obserwacja wczesna i odległa. Wyniki na podstawie badania INJECT.
    Autorzy: Stępińska Janina, Sadowski Zygmunt, Szajewski Tomasz, Banaszewski Marek, Wojciechowski Dariusz, Kraska Tadeusz, Nartowicz Edmund, Kuch Jerzy
    Źródło: Kardiol. Pol. 2002: 57 (12) s.512-519, tab., bibliogr. 16 poz. - 196 Kongres Europejskiego Towarzystwa KardiologicznegoKongres nt. niewydolności serca SztokholmGenewa 19971998 - Tekst równol. w jęz. pol.
    Sygnatura GBL: 313,397

    Hasła klasyfikacyjne GBL:
  • toksykologia
  • kardiologia

    Typ dokumentu:
  • praca związana ze zjazdem
  • praca epidemiologiczna

    Wskaźnik treści:
  • ludzie
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background. Short-acting calcium channel blockers (Ca-blockers) have been shown in some studies to increase the risk of myocardial infarction (MI) and post-MI complications. Data from large, international, randomised studies such as the INJECT trial may bring new iportant inforamtion on the effects of medication used before MI, on the course of MI and post-MI complications. Aim. To assess the effects of beta-blocker and Ca-blocker therapy administsered prior to MI on the early and late outcome after MI. Methods. The study group consisted of 6001 patients with acute MI treated according to the INJECT protocol. The patients were divided into four groups according to the type of treatment before the index MI: Group I (n = 580) - patients treated with beta-blockers; Group II (n = 831) - patients treated with Ca-blocker or Ca-blocker treatment. The analysed end-points were 35- and 180-day mortality as well as angina recurrences, occurrece of heart failure, atrial fibrillation/flutter and asystole. Results. During hospital stay, supraventricular arrhythmias, asystole, recurrent ischaemia and heart failure occurred more frequently in patients from groups II and III than in other groups. Early mortality was significantly higher in group II (p 0.001) and group III (p 0.002) than in group IV. Late mortaltiy was the lowest in group IV, followed by group I. Cox proportional hazards multivariable analysis revealed that hypotension, Killip class (V (p 0.001), previous Ca-blocker (p 0.01) or Ca- and beta-blocker treatment (p 0.001) as well as previous MI (p 0.05) were the independent predictors of death. Conclusions. Compared with beta-blocker therapy or no treatment, previous use of Ca-blockers increases both early and long-term complication rates in patients with MI.

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    Tytuł oryginału: Uszkodzenie mięśnia sercowego o niejasnej etiologii przyczyną ustawicznego częstoskurczu z lewej komory wyzwalającego migotanie komór.
    Tytuł angielski: Permanent left ventricular tachycardia degenerating in ventricular fibrillation.
    Autorzy: Szumowski Łukasz, Walczak Franciszek, Koźluk Edward, Kępski Roman, Szufladowicz Ewa, Stępińska Janina, Szajewski Tomasz, Przybylski Andrzej, Szwed Hanna
    Źródło: Kardiol. Pol. 2002: 57 (12) s.597-601, il., bibliogr. 7 poz.
    Sygnatura GBL: 313,397

    Typ dokumentu:
  • praca kazuistyczna

    Wskaźnik treści:
  • ludzie
  • dorośli = 65 r.ż.
  • płeć żeńska

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