Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Transurethral microwave thermotherapy: first experiences in Poland.
Autorzy: Jakubczyk T., Stokłosa A[ndrzej], Borkowski A[ndrzej], Habrat W., Dobrowolski Z[ygmunt F.]
Źródło: Br. J. Urol. 2002: 89 (7) s.767-770, tab., bibiliogr. 21 poz.
Sygnatura GBL: 300,816

Hasła klasyfikacyjne GBL:
  • onkologia
  • urologia

    Typ dokumentu:
  • praca kliniczna
  • praca opublikowana za granicą
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.

    Streszczenie angielskie: Objective: To present early experiences in Poland with high-energy transurethral microwave thermotherapy (HeTUMT), considered as a serious alternative to surgery in managing benign prostatic hypertrophy (BPH). Patients and methods: Sixty-one patients were treated in two centres using a commercial TUMT system. The patients were assessed at 5-6 weeks, 3 and 6 months after treatment, evaluating subjective complaints, the International Prostate Symptom Score (IPSS), urinary flow rate and postvoid residual volume. Results: A complete follow-up was available in 44 patients; most had symptomatic improvement 3 months after HeTUMT but it was slightly less pronounced after 6 months. The improvement in objective variables increased up to 6 months after HeTUMT. There was ň 50 p.c. improvement in subjective complaints in 43 p.c. of the patients, in urinary flow rate in 25 p.c. and in residual urine in half. Two patients required re-treatment for a urethral stricture and ineffective HeTUMT. Conclusions: HeTUMT may be a useful treatment for BPH but the outcome for an individual patient seems to be unpredictable. The indications for TUMT should be reviewed individually for each patient.

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    Tytuł oryginału: Immunologia
    Autorzy: Gaciąg Zbigniew, Gołąb Jakub, Grzesiowski Paweł, Hryniewicz Waleria, Jakóbisiak Marek, Kamiński Rafał, Korczak-Kowalska Grażyna, Kozar Katarzyna, Kurpisz Maciej, Lasek Witold, Majewski Sławomir, Malejczyk Jacek, Obłąkowski Piotr, Olszewska Dominika, Płoski Rafał, Radkowski Marek, Stokłosa Tomasz, Wańkowicz-Kalińska Anna, Zagożdżon Radosław
    Opracowanie edytorskie: Gołąb Jakub (red.), Jakóbisiak Marek (red.), Lasek Witold (red.).
    Wydanie: - Wyd. nowe (4 zm.)
    Źródło: - Warszawa, Wydaw. Naukowe PWN SA 2002, XXIII, [1], 567, [1] s. : il., tab., 28 cm.
    Sygnatura GBL: 802,198

    Hasła klasyfikacyjne GBL:
  • immunologia

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    Tytuł oryginału: Angiotensin I-converting enzyme and chymase gene polymorphisms - relationship to left ventricular mass in type 2 diabetes patients.
    Autorzy: Gumprecht Janusz, Zychma Marcin, Grzeszczak Władysław, Łącka Beata, Burak Wacław, Mosur Mariusz, Kaczmarski Jacek, Otulski Ireneusz, Stokłosa Tomasz, Czank Piotr
    Źródło: Med. Sci. Monitor 2002: 8 (8) s.CR603-CR606, tab., bibliogr. 31 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • genetyka
  • endokrynologia
  • kardiologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: Type 2 diabetic patients are at increased risk for cardiovascular morbidity and mortality. Increased left ventricular mass also predicts a higher incidence of cardiovascular events. Angiotensin II is a potent mediator of myocardial growth, and angiotensin II can be produced in the heart by angiotensin I-convertig enzyme (ACE) and heart chymase (CMA). The aim of this study was to establish the role of ACE gene insertion/deletion (I/D) and CMA gene CMA/B polymorphisms in determining left ventricular mass in type 2 dibetic patients. Material/Methods: Echocardiographic measurements, ACE gene I/D and CMA/B genotypes were determined in 154 type 2 daibetic patients. Results: Mean LVMI was higher among DD homozygotes compared to heterozygotes and II homozygotes (128.9 g/mý vs. 120.5 g/mý and 120.4 g/mý, respectively), but the difference was not statistically significant (ANOVA P = 0.12). A similar effect was observed for the CMA/B polymorphism, where mean LVMI were 126.6 g/mý, 122.1 g/mý adn 118.2 g/mý, for carriers of AA, AG and GG genotype, respectively (not statistically significant, P = 0.33). ACE I/D adn CMA/B polymorphism were also analyzed jointly, and carriers of both DD and AA genotypes were found to have significantly higher LVMI values (P = 0.05) than non-carriers (133.0 g/mý and 121.2 g/mý, for 21 DD and AA carriers vs. 133 non-carriers). In multivariate analysis, the presence of DD and AA genotpyes was independently associated with LVMI (P = 0.04). Conclusion: Our results may suggest the additive effect of ACE and CMA gene polymorphisms on the increase in left ventricualr mass in NIDDM patients.

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