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Tytuł oryginału: Thermal effect of intravascular MR imaging using an MR imaging-guidewire: an in vivo laboratory and histopahtolgical evaluation.
Autorzy: Yang Xiaoming, Yeung Christopher J., Ji Hongxiu, Serfaty Jean-Michel, Atalar Ergin
Źródło: Med. Sci. Monitor 2002: 8 (7) s.MT113-MT117, il., tab., bibliogr. 16 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • radiologia
  • hematologia
  • kardiologia

    Typ dokumentu:
  • badanie porównawcze
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • króliki

    Streszczenie angielskie: Background: Intravascular magnetic resonance (MR) imaging to guide interventional procedures is a rapidly growing field. A primary concern with these new techniues is their thermal safety. The purpose of this study was to evaluate, in vivo, the thermal effect of an MR imagingguidewire (MRIG) for intravascular MR imaging (IV MRI). Material/Methods: Two indications of potentially adverse local heating were investigated: blood coagulation disorders and pathologica changes in target vessels. Experiments were performed on ten rabbits with a 1.5 T MR scanner. Using a 0.64-mm MRIG as the RF receiver, we imaged the target aorta using a fast spin-echo pulse sequence with an average spcific absorption rate (SAR) of 0.6 W/kg. The total MR imaging time was approximately 70 minutes. Results: There were no abnormal value changes of the coagulation factors between pre- and post-IV MRI, no clinical manifestations of blood coagulation disorders, and, histopathologically, no thermal damage in target vessels. Conclusions: This study demonstrates, from a pathophysiological point of view, the potenial safe use of the MR imaging-guidewire for intravascular MR imaging. Further study is required to precisely define the boundaries of these safe operating parameters.

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