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Zapytanie: SCHULTZ
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Tytuł oryginału: Modulation of pulmonary innate immunity during bacterial infection - animal studies.
Autorzy: Schultz Marcus J., Poll Tom van der
Źródło: Arch. Immunol. Ther. Exp. 2002: 50 (3) s.159-167, il., tab., bibliogr. 68 poz.
Sygnatura GBL: 304,223

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • pulmonologia

    Typ dokumentu:
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta

    Streszczenie angielskie: Both the increasing number of immunocompromised patients susceptible to pneumonia and the development of bacterial resistance are sgnificant problems related to the treatment of pneumonia. The primary outcome of treatment for pneumonia is to tip tha balance a successful host response. An ideal approach would be a combination of immunomodulayion and conventional antimicrobial therapy. It is of increasing imoprtance to understand the components of innate immunity, before immunomodulatory therapy can be applied to patients. Much of our knowledge of the role of alveolar macrophages, cytokines and chemokines in the pathogenesis of pneumonia is derived from animal studies on experimental pneumonia. This article summarizes current information on the role of an alveolar macrophage (AM) and AM-derived mediators in host defense against pneumonia.

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