Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Borna Disease Virus - reactive antibodies in Polish psychiatric patients.
Autorzy: Rybakowski Filip, Sawada Takashi, Yamaguchi Kazunari, Rajewski Andrzej, Rybakowski Janusz
Źródło: Med. Sci. Monitor 2002: 8 (9) s.CR642-CR646, tab., bibliogr. 23 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • psychiatria i psychologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: It has been proposed that the Borna Disease Virus (BDV) plays a role in the etiopathogenesis of psychiatric disorders. We assessed BDV seropositivity in Polish psychiatric patients and healthy controls, and the relationship between seropositivity and selected diagnostic and clinical variables. Material/Methods: Serum samples from 946 psychiatric patients with different diagnoses (ICD-10) and 407 psychiatrically healthy controls were assayed. The ECLIA method was used, which enables the assessment of two anti-BDV antibodies: anti-p24 and anti p-40. Data were also collected on diagnosis, age, age at onset, and place of residence. Results: Only anti-p24 antibodies were found. The seropositivity rates were: 2.4 p.c. and 1.0 p.c., respectively, in patients and controls (p = 0.1). A significant difference between patients and controls was observed in mental retardation and affective-anxiety spectrum disorders. Seropositivity did not show any association with demographic variables, but it was elevated in patients with recent onset of disease vs. remote onset of disease (10.2 p.c. vs. 1.6 p.c.; p = 0.0003). Conclusions: Significantly higher anti-BDV seropositivity was found in Polish psychiatric patients with affective-anxiety spectrum disorders and mental retardation than in controls. The association between recent onset disorders and higher anti-BDV response, in the light of recent reports on circulating immune complexes of BDV antigens and antibodies, warrants furhter studies on the longitudinal course of humoral response to BDV.


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    Tytuł oryginału: Detection of anti-Borna Disease Virus antibodies in patients hospitalized in psychiatric hospitals situated in the mid-western region of Poland.
    Autorzy: Rybakowski Filip, Yamaguchi Kazunari, Krzymiński Stefan, Zmyślony Franciszek, Biernat Jerzy, Kociałkowski Marek, Tandeck Andrzej, Trafarska Barbara, Zalejski Marian, Sawada Takashi, Naraki Tohru, Czerski Piotr, Rajewski Andrzej, Rybakowski Janusz K.
    Źródło: Arch. Psychiatr. Psychother. 2002: 4 (3) s.47-54, tab., bibliogr. 38 poz.
    Sygnatura GBL: 313,554

    Hasła klasyfikacyjne GBL:
  • psychiatria i psychologia
  • mikrobiologia

    Typ dokumentu:
  • praca epidemiologiczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: The seroprevalence of anti-Borna Disease Virus antibodies in the population of patients hospitalised in psychiatric hospitals of mid-western Poland was assessed with the ACLIA methos.

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