Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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1/5

Tytuł oryginału: Autoaggregation, hydrophobic, and hydrophylic properties of Moraxella catarrhalis strains.
Autorzy: Janicka Grażyna, Mikucka Agnieszka, Sękowska Alicja, Zwierzchlewski Tomasz, Wróblewski Marcin
Źródło: Acta Microbiol. Pol. 2002: 51 (1) s.23-30, il., bibliogr. [27] poz.
Sygnatura GBL: 302,697

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • pulmonologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • in vitro

    Streszczenie angielskie: The hydrophobicity of the bacterial cell surface was evaluated via the salt aggregation test (SAT) in 58 strains (19 from the lower and 39 from the upper respiratory tracts) of Moraxella catarrhalis in hospitalized patients aged 25 to 65. Based on the SAT results, the strains were divided into three groups: autoaggregating (highly hydrophobic), hydrophobic, and hydrophilic. At a temperature of 37řC, the autoaggregating, hydrophobic or hydrophilic properties did not depend on the choice of a medium, whereas at 22řC the investigated properties did (p 0.0001). Taking into account the origin of the strains (lower vs. upper respiratory tract), it was found that: in the strains cultivated in liquid medium, both highly hydrophobic, hydrophobic and hydrophilic surfaces were present with a comparative frequency, independent of the strain isolated site and cultivation conditions; strains with highly hydrophobic and hydrophobic surfaces, but only those cultivated on solid media at 22řC, were much more often isolated from sputum rather than from nose and throat swabs, whereas a ststistically significant incidence of hydrophilic strains was found in samples from the uppeer rather than lower respiratory tract.

    2/5

    Tytuł oryginału: Aortalna ekspresja genu białka chemotaktycznego monocytów typu 1 (MCP-1) u królików z doświadczalną miażdżycą : praca doktorska
    Autorzy: Sękalska Beata, Ciechanowicz Andrzej (promot.).; Pomorska Akademia Medyczna Samodzielna Pracownia Patobiochemii i Biologii Molekularnej w Szczecinie
    Źródło: 2002, 97 k. : il., tab., bibliogr. 133 poz., streszcz., maszyn.
    Sygnatura GBL: 45/19837

    Hasła klasyfikacyjne GBL:
  • genetyka
  • kardiologia

    Typ dokumentu:
  • praca doświadczalna
  • praca doktorska

    Wskaźnik treści:
  • zwierzęta
  • króliki

    3/5

    Tytuł oryginału: The proactive coping inventory - Polish adaptation.
    Autorzy: Pasikowski Tomasz, Sęk Helena, Greenglass Esther, Taubert Steffen
    Źródło: Pol. Psychol. Bull. 2002: 33 (1) s.41-46, tab., bibliogr. [5] poz.
    Sygnatura GBL: 305,458

    Hasła klasyfikacyjne GBL:
  • psychiatria i psychologia

    Typ dokumentu:
  • praca przeglądowa

    Streszczenie angielskie: The paper concerns a new measure of coping: the Proactive Coping Inventory (PCI). In the first polish version of the PCI used in the study of Canadian-Polish sample was rather an experimental one. It was necessary to work out a new translation of the inventory. the team of researchers created a collective version based on these two translations. The new adaptation was proof on a Polish sample of 220 students; 193 females and 27 males; age ranged from 19 to 50, mean age was 25.19. Besides the PCI, Beck Depression Inventory and the Health Profile Scale were included in the set of measures. The results shows the mean result of the subscales of PCI, and of the items too. The intercorrelations of the scale were presented. The psychometric properties of the new Polish version of the Proactive Coping Inventory obtained in the present study are comparable to the results obtained from the original Canadian sample. It means that despite the cross-cultural differences, the inventory follows a similar course. The results also indicate that the Polish adaptation is a good equivalent of the original measure. This measure can be used in development of the theory of proactive coping with life stress.

    4/5

    Tytuł oryginału: Resistance of Klebsiella pneumoniae strains producing and not producing ESBL (extended-spectrum beta-lactamase) type enzymes to selected non-beta-lactam antibiotics.
    Autorzy: Sękowska Alicja, Janicka Grażyna, Kłyszejko Czesław, Wojda Małgorzata, Wróblewski Marcin, Szymankiewicz Maria
    Źródło: Med. Sci. Monitor 2002: 8 (3) s.BR100-BR104, il., tab., bibliogr. 33 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • farmacja

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Background: Bacteria of the Klebsiella genus may cause numerous infections in human, which are often treatead with beta-lactam antibiotics. The fundamental mechanism of Klebsiella resistance to penicillns or cephalosporins involves the production of enzymes - extended-spectrum beta-lactamases (ESBLs). Because of resistance of many Klebsiella spp. strains to beta-lactams, alternative antibiotic therapy can make use of aminoglycosides and quinolones. Material/Methods: The study analyzed the prevalence of ESBL - type enzymes among 256 Klebsiella pneumoniae strains isolated from various clinical materials collected from patients hospitalized between 1997 and 2000. ESBLs were detected by double-disk synergy test (DDST). The prevalence of strains resistant to selected aminoglycosides (gentamicin, amikacin, netilmicin) and quidolones (ciprofloxacin, norfloxacin, nalidixic acid) in the particular years was analysed. Drug sensitivity was determined by disk-diffusion method according to the recommendations of the National Reference Center for Microbial Drug Sensitivity. Results: During the analyzed time interval, a significant increase of the number of K. pneumoniae ESBL(+) strains was noted: in 1997 - 16.5 p.c. (14/85) and in 2000 - 40.4 p.c. (22/54) (p 0.001). Among the ESBL (+) strains, an increase of the number of starins resistant to the tested antibiotics, excepto for anlidixic acid, was demonstrated. Conclusion: A statistically significant increase of multidrug-resistant K. pneumoniae strains, including strains producing ESBLs, was demosntrated in the analyzed material.

    5/5

    Tytuł oryginału: Ekspresja genów klonowanych w wektorach plazmidowych w zrekombinowanych szczepach Escherichia coli.
    Tytuł angielski: Expresion of genes cloned in plasmid vectors in recombinant Escherichia coli strains.
    Autorzy: Sęktas Marian
    Źródło: Kosmos 2002: 51 (3) s.365-373, il., tab., bibliogr. [25] poz., sum.
    Sygnatura GBL: 313,370

    Hasła klasyfikacyjne GBL:
  • genetyka
  • mikrobiologia

    Streszczenie angielskie: Use of Escherichia coli bacteria as a host for high-level expression of cloned genes has become common. The purfication of a recombinant protein is greatly accelerated if the protein can be isolated from cells that overproduce it. To maximize expression, the cloned gene must be transcribed and translated as efficiently as possible. This is possible due to the construction of expression vectors, modified plasmids with useful features, which can be propagated and controlled in special hosts (expression systems). Usually, vectors for cloning and expressing targer-DNA are derived from medium-copy plasmids like pBR322. E. coli expression systems should meet several criteria including (i) minimal basal expression of the gene to be expressed under repressed conditions, (ii) fast and uncomplicated induction of a wide variety of genes to a high level of expression, and (iii) easy cloning and DNA manipulation features. This article describes how the most common T7 expression system, derived from bacteriophage T7, functions The system consists of a plasmid vector that allows coloning of the target DNA under T7 promoter control, and the T7 RNA polymerase gene borne by the recombinant bacterial host. The system is capable of expressing a wide variety of DNAs from prokaryotic and eukaryotic sources. In principle, the T7 system can be completely selective because host RNA polymerase and phage's polymerase recognized different promoters. However, synthesis of recombinant proteins, especially those that are toxic to the host, must be controlled, being at zero or non-toxic levels...

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