Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: ROJO
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: The TCR/CD3 complex: molecular interactions in a changing structure.
Autorzy: Feito Maria Jos‚, Jim‚nez-Perianez Arturo, Ojeda Gloria, Sanchez Alejandra, Portol‚s Pilar, Rojo Jos‚ M.
Źródło: Arch. Immunol. Ther. Exp. 2002: 50 (4) s.263-272, il., bibliogr. 94 poz.
Sygnatura GBL: 304,223

Hasła klasyfikacyjne GBL:
  • immunologia

    Typ dokumentu:
  • tytuł obcojęzyczny

    Streszczenie angielskie: The T cell receptor-CD3 (TCR/CD3) complex is a multichain structure in charge of antigen recognition in T cells. Despite many genetic, structural, and functional data obtained in recent years, essential questions concerning the TCR/CD3 complex still remain open, including: 1) the precise number of polypeptides in each TCR/CD3 complex, their interactions and spatial arrangement, 2) the role(s) of each polypeptide in antigen recognition and/or in receptor signal transmission, and 3) the relationship between the TCR/CD3 complex and other membrane or cytoplasmic molecules involved in downstream signaling. In this work we shall review data concerning some of these issues, proposing a model of the overall structure of the TCR/CD3 complex to explain its known features.

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    Tytuł oryginału: Angiocentric lymphoma - its differentiation with the metastatic lung tumours.
    Autorzy: Michnar Marek, Krawczyk Paweł, Rojowski Andrzej, Milanowski Janusz
    Źródło: Centr. Eur. J. Immunol. 2002: 27 (2) s.49-52, il., bibliogr. 12 poz.
    Sygnatura GBL: 313,243

    Hasła klasyfikacyjne GBL:
  • onkologia

    Typ dokumentu:
  • praca kazuistyczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska

    Streszczenie angielskie: Angiocentric T-cell lymphoma (described by Liebow as lymphomatoid granulomatosis), which typically involves nose and upper respiratory system, is mostly a multisystemic disease. We report a 27-year-old patient with multiple lesions in both lungs in chest X-ray and CT images resembling the metastatic tumour of the lung. The immunophenotype of 74.5 p.c. of T-lymphocytes from BALF was CD3+, CD4+, CD8+, CD45RO+, CD56-, and CD4/CD8 ratio had a value of 0.26. The diagnosis of angiocentric lymphoma in this patient was confirmed by a histopatological analysis of the material from thoracotomy. The patient was treated with aggressive, multidrug chemotherapy, but he died 3 months after the beginning of the disease with the symptoms of the DIC syndrome and respiratory insufficiency.

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