Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: PROTAS-DROZD
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Necrobiotic xanthogranuloma.
Autorzy: Protas-Drozd Franciszka, Placek Waldemar, Uchańska Grażyna, Skory Paweł
Źródło: Prz. Dermatol. 2002: 89 (2) s.113-117, il., bibliogr. 14 poz., sum. - 27 Zjazd Polskiego Towarzystwa Dermatologicznego Wrocław 21-24.06. 2001
Sygnatura GBL: 301,248

Hasła klasyfikacyjne GBL:
  • dermatologia i wenerologia

    Typ dokumentu:
  • praca związana ze zjazdem
  • praca kazuistyczna

    Wskaźnik treści:
  • ludzie
  • dorośli 45-64 r.ż.
  • płeć żeńska

    Streszczenie polskie: W pracy przedstawiono przypadek 46-letniej kobiety z necrobiotic xanthogranuloma. Rozpoznanie zostało potwierdzone badaniami histopatologicznymi skóry, stwierdzeniem leukopenii, gammopatii podwyższonego poziomu cholesterolu. Pacjentka była leczona deksametazolem bez poprawy.

    Streszczenie angielskie: A case of 46-year old women with necrobiotic xanthogranuloma was presented. The disease of unknown etiology is a very rare one and belongs to the so called non X-histiocytosis. Clinical diagnosis was confirmed by histopathological examination of the skin biopsy. Apart from skin lesions there were revealed other disturbances: leukopenia, gammopathy and hypercholesterolemy. The patient was treated with dexametazon and no clinical improvement was obtained.

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    Tytuł oryginału: Activity of superoxide dismutase and catalase and the level of lipid peroxidation products reactive with TBA in patients with psoriasis.
    Autorzy: Drewa Gerard, Krzyżyńska-Malinowska Ewa, Woźniak Alina, Protas-Drozd Franciszka, Mila-Kierzenkowska Celestyna, Rozwodowska Małgorzata, Kowaliszyn Bogna, Czajkowski Rafał
    Źródło: Med. Sci. Monitor 2002: 8 (8) s.BR338-BR343, tab., bibliogr. 34 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • dermatologia i wenerologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: The etiology of psoriasis, one of the most common chronic dermatoses, has not been elucidated yet. Involvement of antioxidant enzymes is suspected. The study aimed to determine the concetrations of lipid pereoxidation products reactive with thiobarbituric acid and antioxidant enzymes activity. Material/Methods: 67 patients of the Chair and Clinic of Dermatology (22 females and 45 males) with psoriasis vulgaris of 3 to 34 years' duration were examined. All were treated topically with preparations for external use. Smooth skin was treated with salicyl ointment, cignoline and tar, while salicyl oil and betamethasone diproproionide with salicylic acid was used on the scalp. Lipid peroxidation products reactive with TBA, expressed as malondialdehyde (MDA) concentration, were determined in erythrocytes using Buege and Aust method. Activities of antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT), were determined in erythrocytes according to Misra and Fridovich, and Beers adn Sizer, respectively. Results: In halthy subjects, SOD and CAT activity was 1049.2 ń 261.9 U/gHb and 41.4 ń 13.7 x 10**4 IU/gHb, respectively, and MDA concentration 35.8 ń 10.5 nM/gHb. MDA concentrations in erythrocytes of psoriatic patients before treatment were 44 p.c. higher and SOD and CAT activities 20 p.c. and 27 p.c. lower, respectively, than those observed in the controls. Topical treatment improved the patients' clinical condition, resulting in slow increase of enzyme activity to values comparable with controls. Conclusions: The results confirm the involvement of antioxidant enzymes in the pathogenesis of psoriasis. It is, however, questionable whether the observed abnormalities are responsible for the onset of psoriasis, or resultant from ongoing pathologic process.

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