Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: PROSIŃSKA
Liczba odnalezionych rekordów: 3



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Tytuł oryginału: Investigations of the thymomimetic activity of a selected phytopharmaceutical preparation - reumaherb tablets by flow cytometry.
Autorzy: Prosińska Joanna, Sawicka Teresa, Drozd Janina
Źródło: Acta Pol. Pharm. 2002: 59 (4) s.265-273, il., tab., bibliogr. 25 poz.
Sygnatura GBL: 301,378

Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • myszy
  • in vitro

    Streszczenie angielskie: The aim of the present study was to investigate the influence of Reumaherb tablets, a plant preparation, on th ematuration of mice thymocytes in the presence of glycocorticosteroid by the method of cytotoxicity test performed in vitro in two versions differing in methodology. The cell source for incubation was thymus of female Balb/c mice, four weeks old. Reumaherb tablets were added to the culture of thymocytes diluted by a factor of 10-400. The searched thymomimetic activity of the investigated Reumaherb preparation was found in both versions of the test, this being demonstrated by a 17 p.c. increase in the number of surviving cells in the presence of glycocorticosteroid added to the culture. This effect strongly depends on the applied doses. By a microscopic evaluation of the results a maximum stimulation was found at a 200-fold dilution of the examined preparation, while in the cytometric analysis a similar maximum effect was observed at a 20-fold dilution.

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    Tytuł oryginału: Działanie immunotropowe destylatu borowiny limanu z dodatkiem kwasu cynamonowego i kumaryny (FIBS).
    Tytuł angielski: Immunotropic activity of coastal salt lake mud distillate mixed with cinnamic acid and coumarin (FIBS).
    Autorzy: Skopiński Piotr, Sawicka Teresa, Drozd Janina, Prosińska Joanna, Białas-Chromiec Beata, Różewska-Skopińska Ewa
    Źródło: Okulistyka 2002: 5 (4) s.71-74, 76, il., tab., bibliogr. 19 poz., sum.
    Sygnatura GBL: 313,465

    Hasła klasyfikacyjne GBL:
  • farmacja
  • immunologia

    Typ dokumentu:
  • praca doświadczalna

    Wskaźnik treści:
  • zwierzęta

    Streszczenie angielskie: FIBS an aqueous solution of biogenic stimulators, elaborated in 1948 year by prof. V.P.Filatov team, was successfully employed in medical practice, especially in ophthalmology. The aim of the present study was to evaluate, on mice experimental model, the effect of FIBS on some parameters of cellular and humoral immunity and on the inflammatory angiogenesis induced in conjunctiva by TRITON. We observed stimulation of cellular and humoral immune response in mice treated with FIBS, both after oral and subcutaneous administration, and suppression of inflammatory angiogenic response to TRITON. Conclusion: FIBS treatment may be valuable in diseases of inflammatory origin and in the states of impairment of immune response.

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    Tytuł oryginału: Estimation of humoral activity of eleutherococcus senticosus.
    Autorzy: Drozd Janina, Sawicka Teresa, Prosińska Joanna
    Źródło: Acta Pol. Pharm. 2002: 59 (5) s.395-401, il., tab., bibliogr. 15 poz.
    Sygnatura GBL: 301,378

    Hasła klasyfikacyjne GBL:
  • immunologia
  • farmacja

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • myszy
  • płeć żeńska

    Streszczenie angielskie: The aim of the present work was an estimation of the influence of two plant pharmaceutical preparations containing an extract from the root of Eleutherococcus senticosus: Argoeleuter tablets and Immuplant tablets, on the humoral response of immunological system. Experiments were performed with female Balb/c mice six weeks old. In order to reveal the influence of taking preparations, containing an extract from Eleutherococcus senticosus on some elements of the immunological system, three ways of their administration have been compared: before illness, during illness and a combination of both. The obtained results allow formulating the following conclusions: -the pharamceutical preparations, containing the extract from Eleutherococcus senticosus administered orally, influence on the increase of the level of immunoglobulins comprised in the mice's blood serum, -the pharmaceutical preparations act with different power, not fully dependent on the content of marker of the active substance - eleutheroside E, -dosage of the preparations containing the extract from Eleutherococcus senticosus should not be estabilished basing only on the extract content, -best curative results, measured as the stimulation of humoral response of the organism were obtained when a given preparation was administered therapeutically, even though the combined administration - prophylactically with prolonged administration during illness also is correct.

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