Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Effect of combined dopamine and diltiazem on renal function after cardiac surgery.
Autorzy: Yavuz Senol, Ayabakan Nurcan, Goncu M. Tugrul, Ozdemir I. Ayhan
Źródło: Med. Sci. Monitor 2002: 8 (5) s.PI45-PI60, il., tab., bibliogr. 16 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • chirurgia
  • farmacja
  • kardiologia
  • nefrologia

    Typ dokumentu:
  • praca kliniczna
  • badanie porównawcze
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: In order to evaluate the effect of the combined use of dopamine and diltiazem on renal function in patients undergoing coronary artery bypass grafting (CABG), we conducted a prospective randomized study. Sixty patients (8F, 52M) with normal preoperative renal function undergoing CABG were divided randomly into four groups, including control (n = 15), use of dopamine-only (n = 15), use of diltiazem-only (n = 15), and combined use of dopamine and diltiazem (n = 15). The patients ranged in age from 38 to 74 years (mean 59.3). Drug administration (diltizem: intravenous infusion of 2 ćg kg-1.min-1, dopamine: 2 ćgúkg-1.min-1) was initiated 24 hours before surgery and was continued for 72 hours. Creatinine and osmotic clearances were found to be significantly higher in the combined group compared with the other groups 24 hours after surgery (p 0.05). There was no significant difference in respect to creatinine clearance, osmotic clearance, and free water clearance in the dopamine-only and diltiazem-only groups compared to the control group. The free water clearance at 24 and 72 hours after surgery were significantly higher in the combined group compared with the other groups (p 0.05). In the control group, dopamine-only, and diltiazem-only groups á2-microglobulin was statistically higher 72 hours postoperatiave than preoperatively (p 0.050). There were no significant changes in á2-microglobulin levels in the combined group. The combined use of dopamine and diltiazem may provide a positive contribution and sufficient protection for early postoperative renal function in patients undergoing CABG.

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    Tytuł oryginału: The renin-angiotensin-aldosterone system (RAAS) and its relation with calcium homeostasis in male obesity.
    Autorzy: Ozata Metin, Durmus Oziem, Yilmaz Mahmut Ilker, Bolu Erol, Erdogan Murat, Ozdemir I. Caglayan
    Źródło: Med. Sci. Monitor 2002: 8 (6) s.CR430-CR433, tab., bibliogr. 23 poz.
    Sygnatura GBL: 313,278

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska

    Streszczenie angielskie: The aim of our study was to determine whether alterations of the vitamin D-endocrine system and the renin-angiotensin-aldosterone system occur in male obesity and influence each other. 32 ibese male subjects and 21 age-matched healthy male subjects were enrolled in the study. The parameters measured included serum total calcium (Ca), ionized calcium, magnesium (Mg), phosphorus (P), 25-hydroxyvitamin D (25-OHD), supine and upright aldosterone and renin activity, and urinary calcium, magnesium, and phosphorus. Serum total Ca and ionized calicum were slightly, but not significantly lower in obese subjets compared to controls, whereas serum magnesium phosphorus and PTH levels were significantly higher in the obese subjects. Mean urinary calcium and Mg were not significantly different, while urinary P was significantly higher in obese subjects. Mean serum 25OHD was significantly lower in obese subjects. Supine and upright aldosterone and renin were unrelated to BMI or fat mass. Supine aldosterone correlated with serum total calcium, ionized calcium and supine renin activity, but not with other minerals, PTH or 25OHD, whereas upright aldosterone did not correlate with other parameters. Supine renin activity did not correlate with any parameters, whereas upright renin correlated with serum Mg an PTH. There were significant correlations between PTH and BMI or fat mass. Urinary Mg was also related to both BMI and fat mass. Male obesity is associated with increased serum Mg, P, PTH and urinary P and lower supine aldosterone and 25OHD, but unchanged serum and urinary Ca.

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