Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: NIEZNAŃSKI
Liczba odnalezionych rekordów: 3



Przejście do opcji zmiany formatu | Wyświetlenie wyników w wersji do druku

1/3

Tytuł oryginału: The effects of the interaction of myosin essential light chain isoforms with actin in skeletal muscles.
Autorzy: Nieznańska Hanna, Nieznański Krzysztof, Stępkowski Dariusz
Źródło: Acta Bioch. Pol. 2002: 49 (3) s.709-719, il., tab., bibliogr. 717-719
Sygnatura GBL: 303,116

Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • króliki

    Streszczenie angielskie: In order to compare the ability of different isoforms of myosin essential light chain to interact with actin, the effect of the latter protein on the proteolytic susceptibility of myosin light chains (MLC-1S and MLC-1V - slow specific and same as ventricular isoform) from slow skeletal muscle was examined. Actin protects both slow muscle essential light chain isoforms from papain digestion, similarly as observed for fast skeletal muscle myosin (Nieznańska et al., 1998, Biochim. Biophys. Acta 1383: 71). The effect of actin decreases as ionic strength rises above physiological values for both fast and slow skeletal myosin, confirming the ionic character of the actin - essential light chain interaction. To better understand the role of this interaction, we examined the effect of synthetic peptide spanning the 10-amino-acid n-terminal sequences of myosin light chain 1 from fast skeletal muscle (MLC-1F0 (MLCFpep: KKDVKKPAAA), MLC-1S (MLCSpep: KKDVPVKKPA) and MLC-1V (MLCVpep: KPEPKKDDAK) on the myorfibrillar ATPase of fast and slow skeletal muscle. In the presence of MLCFpep, we observed an about 19 p.c. increase, and in the presence of MLCSpepabout 36 p.c. increase, in the myofibrillar ATPase activity of fast muscle. On the other hand, in myofibrillar preparations from slow skeletal muscle, MLCSpep as well as MLCVpep caused a lowering of the ATPase activity by about 36 p.c. The above results suggest that MLCSpep induces opposite effects on ATPase activity, depending on the type of myofibrils, but not through its specific N-terminal sequence - which differs from other MLC N-terminal peptides...


    2/3

    Tytuł oryginału: Przetwarzanie kontekstu i monitorowanie źródła informacji w schizofrenii.
    Tytuł angielski: Processing of context and source of information monitoring in schizophrenia.
    Autorzy: Nieznański Marek
    Źródło: Psychiatr. Pol. 2002: 36 (5) s.731-743, bibliogr. 53 poz., sum., rez., Zsfg, r‚s.
    Sygnatura GBL: 305,130

    Hasła klasyfikacyjne GBL:
  • psychiatria i psychologia

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Recent research has suggested that deficit in the processing of context could be responsible for various impairments in cognitive functioning observed in schizophrenia. Source monitoring, an ability closely related to memory for context, seems to be one of the most important correlates of positive symptoms, especially auditory hallucinations and delusions of alien control.


    3/3

    Tytuł oryginału: Ocena efektywności treningu umiejętności poznawczych w schizofrenii.
    Tytuł angielski: Effectiveness of cognitive skills training in schizophrenia.
    Autorzy: Nieznański Marek, Czerwińska Monika, Chojnowska Agnieszka, Walczak Sławomir, Duński Witold
    Źródło: Psychiatr. Pol. 2002: 36 (5) s.745-757, tab., bibliogr. 50 poz., sum., rez., Zsfg, r‚s.
    Sygnatura GBL: 305,130

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Aim: This study evaluated methods for improving cognitive skills of patients with schizophrenia. Method: Subjects in the experimental group received 12 sessionsof practice with various cognitive tasks, while patients in the control group participated in sessions of psychoeducation. Results: Cognitive assessment before and after the study phase showed that patients in the experimental group had made significantly more improvement than the control group. Both groups improved on the insight scores, however reductions in the level of psychopathology were less tangible.

    stosując format: