Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL
Zapytanie:
MORAL
Liczba odnalezionych rekordów:
2
Przejście do opcji zmiany formatu
|
Wyświetlenie wyników w wersji do druku
1/2
Tytuł oryginału:
Contrast echocardiography and medical economics: looking into the crystal ball.
Autorzy:
Distante
A.,
Dankowski
R.,
Mincarone
P.,
Leo
C. G.,
Gianicolo
E.,
Voci
P.,
Morales
M. A.,
Rovai
D.
Źródło:
Eur. Heart J. 2002: 4 supl. C s.C39-C47, tab., bibliogr. 78 poz.
Sygnatura GBL:
306,213
Hasła klasyfikacyjne GBL:
ekonomika
kardiologia
Typ dokumentu:
praca opublikowana za granicą
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
Streszczenie angielskie:
The past decade has witnessed the development of contrast echocardiography. This technique has demonstrated clinical utility in some applications and extremely promising results have been reported for others, although there are still several obstacles to its acceptance by regulatory authorities and routine users. In addition, the eficacy and cost-effectiveness must be proven against 'gold standard' techniques, which in several cases are just accepted standards. Furthermore, the competition is quite strong both between new techniques and with established ones, and all of the imaging modalities need to find their most appropriate role within this comples environment.
2/2
Tytuł oryginału:
Chronic alpha1-adrenergic blockade improves hypertension and renal injury in L-NAME and low-renin L-NAME-DOCA hypertensive rats.
Autorzy:
Wangesteen
Rosemary,
O'Valle
Francisco,
Moral
Raimundo G. Del,
Vargas
Flix,
Osuna
Antonio
Źródło:
Med. Sci. Monitor 2002: 8 (9) s.BR378-BR384, il., tab., bibliogr. 25 poz.
Sygnatura GBL:
313,278
Hasła klasyfikacyjne GBL:
farmacja
kardiologia
nefrologia
Typ dokumentu:
tytuł obcojęzyczny
praca doświadczalna
Wskaźnik treści:
zwierzęta
szczury
płeć męska
Streszczenie angielskie:
Background: The present study investigated the contribution of ŕ1-adrenergic blockade to hypertension induced by long-term blockade of nitric oxide and chronic treatment with deoxycorticosterone acetate (DOCA), which produced a low renin model of hypertension. We studied the effects of chronic administration of prazosin, an ŕ1-receptor antagonist, on blood pressure (BP), renal injury, and other variables in Nomega-nitro-L-arginine methyl ester (L-NAME) and L-NAME+DOCA hypertensive rats. Material/methods: The rats were divided into 6 groups: Control, DOCA, L-NAME, L-NAME+DOCA, L-NAME+prazosin, and L-NAME+DOCA+prazosin. Tail systolic BP was measured twice a week. After a 6-week evolution, mean arterial pressure (MAP) was measured, along with selected metabolic, morphological and renal variables. Results: The final MAP values were 105 ń 1 for Control, 107 ń 0.6 for DOCA, 153 ń 3 for L-NAME, 175 ń 2 for L-NAME+DOCA, 126 ń 2 for L-NAME+prazosin and 127 ń 5 for L-NAME+DOCA+prazosin. Proteinuria and hyaline arteriopathy were prevented in L-NAME+prazosin rats and markedly attenuated int eh L-NAME+DOCA+prazosin group. Plasma urea and creatinine were significantly increased in teh L-NAME+DOCA group, but not in the L-NAME+DOCA+prazosin group as against controls. The DOCA and DOCA+L-NAME groups showed relative renal and cardiac hypertrophy, which was not observed in teh DOCA+L-NAME+prazosin group. Cocnlusions: ŕ1-adrenergic tone plays and important role in the increased BP and renal injury of L-NAME hypertension. Our results also indicate that when PRA is suppressed by DOCA in L-NAME hypertension, the increased BP and renal injury are largely dependent on the ŕ1-adrenergi tone.
stosując format:
z abstraktem i deskryptorami
z abstraktem
z deskryptorami
skrócony