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Tytuł oryginału: Monitoring of genotoxic risk in industrial areas with an example Rużomberok papermill and factory.
Autorzy: Micieta Karol, Murin Gustav, Kunova Katarina, Halasova Erika, Bukovska Eva
Źródło: Prz. Epidemiol. 2002: 56 supl.: Conference on molecular epidemiology in preventive medicine - achievements and new challenges s.115-121, tab., bibliogr. 18 poz. - Konferencja pt. Molekularna epidemiologia w medycynie prewencyjnej - osiągnięcia i nowe wyzwania Kraków 20-22.06. 2002
Sygnatura GBL: 301,250

Hasła klasyfikacyjne GBL:
  • toksykologia
  • ochrona środowiska
  • genetyka

    Typ dokumentu:
  • praca związana ze zjazdem
  • tytuł obcojęzyczny
  • badanie porównawcze
  • praca epidemiologiczna
  • praca doświadczalna

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Objectives: To compare sensitivity of plant cell bioindication assay with human cell screening method on the example of heavy polluted area around papermill plant. Design: Two-year screening of bioindication effect at cytogenitc level of plant as well as human cells by regular sampling from three sites near the source of pollution and one control site. Setting: City Rużomberok is one of 12 air polluted areas in Slovakia, that according the Ministry of the Environment's of Slovak Republic needs special air protection. And this aim, consequently, needs serious screening of the impact of emission produced on living cells. Main outcome measure: Frequency of aborted/altered pollen grains and chromosomal aberations in peripheral lymphocytes in blood samples of children living in neighbourhoods of papermill plant. Results: From the 12 plant species analysed, significant difference from the control samples were found in frequency and occurrence of abortive an danomalous microspores and pollen grains among 9 species in year 1999 and 8 species in year 2000. They were: Pinus sylvestris L., Robinia pseudoacacia L., Corylus avellana L., Linaria vulgaris Mill., Melilotus albus Medik., Trifolium pratense L., Calystegia sepium R.Br., Chelidonium majus L., Cichorium intybus L. In the Pinus sylvestris L. samples we observed an increased amount of anomalous (unreducted, 2n, 4n) pollen grains, which represent mutagenity at the genome level. Spontaneous level of chromosomal aberrations in peripheral lymphocytes of children ...

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