Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: MATUSZAK
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Indocyanine green as a prospective sensitizer for photodynamic therapy of melanomas.
Autorzy: Urbańska Krystyna, Romanowska-Dixon Bożena, Matuszak Zenon, Oszajca Janusz, Nowak-Śliwińska Patrycja, Stochel Grażyna
Źródło: Acta Bioch. Pol. 2002: 49 (2) s.387-391, il., bibliogr. [9] poz. - 5 Sympozjum nt. wolnych rodników w biologii i medycynie Łódź 07-10.06. 2000
Sygnatura GBL: 303,116

Hasła klasyfikacyjne GBL:
  • onkologia
  • radiologia
  • farmacja

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca związana ze zjazdem
  • praca doświadczalna

    Wskaźnik treści:
  • ludzie
  • zwierzęta
  • myszy
  • in vitro

    Streszczenie angielskie: Spectroscopic, photochemical and biological properties of indocyanine green (ICG) are presented. Light over 800 nm is effectively absorbed by ICG. This property as well as photochemical behaviour of ICG make it a very suitable dye for photodynamic treatment of melanoma cells. Cytotoxicity of ICG itself and the effect of photodynamic therapy (PDT) were evaluated by following the growth of human (SKMEL 188) and mouse (S91) melanoma cells. The surviving fraction of the cells irradiated (lambda ex = 830nm) vs non-irradiated, treated with the same dose of ICG, is significantly decreased (5- to 10-fold). These results show that ICG is a very promising dye for photodynamic therapy of melanomas.

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    Tytuł oryginału: Characterization of optical properties of some photosensitizers in solution and in tissue-like media. Experiment and Monte Carlo simulation.
    Autorzy: Matuszak Z., Wasilewska-Radwańska M., Skwara A., Rogoda E.
    Źródło: Pol. J. Med. Phys. Engin. 2002: 8 (3) s.135-142, il., bibliogr. 9 poz.
    Sygnatura GBL: 306,499

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Streszczenie angielskie: In the present paper absorption spectra of some classical photosensiterizers such as methylene blue, eosin, fluorescein, hematoporphyrin were measured and simulated using the Monte Carlo method. The days were investigated in a water solution and in the tissue-like medium Intralipid, which is a standarized aqueous fat emulsion with well-defined optical parameters. The results of experiments were used in the Monte Carlo simulations of the light transport in media containing the investigated photosensistizers. The true absorption spectra were calculated from the spectra blurred by scattering. The results of simulation confirmed the possibility of determination within the scattering media, both the kind of the dye and its quantity. This fact is very important in the use of absorption spectroscopy to determine the content of dyes in real biological tissues.

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