Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL
Zapytanie:
LARMORE
Liczba odnalezionych rekordów:
1
Przejście do opcji zmiany formatu
|
Wyświetlenie wyników w wersji do druku
1/1
Tytuł oryginału:
Leptin and estradiol as related to change in pubertal status and body weight.
Autorzy:
Larmore
Kimberly A.,
O'Connor
Darlise,
Sherman
Tami Irwin,
Funanage
Vicky L.,
Hassink
Sandra G.,
Klein
Karen Oerter
Źródło:
Med. Sci. Monitor 2002: 8 (3) s.CR206-CR210, il., tab., bibliogr. 27 poz.
Sygnatura GBL:
313,278
Hasła klasyfikacyjne GBL:
pediatria
ginekologia i położnictwo
Typ dokumentu:
praca kliniczna
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
płeć żeńska
Streszczenie angielskie:
Background: Previous studies have examined the relationship between leptin, body mass, and pubertal status. The present study directly compares the relationship of leptin and estradiol in 5 groups of girls with different combnations of pubertal status and weight. Material/Methods: We studied girls with idiopathic precocious puberty, age-matched non-obese prepubertal girls, age-matched obsese prepubertal girls, normal pubertal girls, and obese pubertal girls (n = 12/group). Results: Leptin levels were significantly higher in obese pubertal girls (26.6 ń 8.4 ng/mL) than in all others. Leptin levels were signifcantly higher in obese prepubertal girls (20.7 ń 10.9 ng/mL) (mean ń SD) compared to girls with precocious puberty (7.7 5.4 ng/mL, p 0.004), non-obese prepubertal girls (5.55 ń 3.6 ng/mL, p 0.001), and normal pubertal girls (4.8 ń 2.9 ng/mL, dard deviation score), which corrects leptin level for gender, pubertal stage, and BMI, was significantly lower in the obese pubertal group than in the 3 non-obese groups. Conclusions: These findings confirm previous studies that body mass, chronolgoical age and pubertal stage are determinants of leptin level. However, these are not the only factors determining leptin level as evidenced by persistent differences in leptin level between obese and non-obese pubertal girls even when correcting for pubertal stage and BMI. While the present study provides no new answers to the question of pubertal regulation, it provides a direct comparison of combination weight, pubertal stage, and leptin level, as background for future studies.
stosując format:
z abstraktem i deskryptorami
z abstraktem
z deskryptorami
skrócony