Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: KUYDOWICZ
Liczba odnalezionych rekordów: 5



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1/5

Tytuł oryginału: Zakażenie CMV czy cytomegalia - problemy diagnostyczne i lecznicze.
Tytuł angielski: Infection with CMV or cytomegaly - diagnostic and therapeutic problems.
Autorzy: Majda-Stanisławska Ewa, Szaflik Iwona, Kuydowicz Jan
Źródło: Post. Mikrobiol. 2002: 41 supl. 1 s.35-38, tab., bibliogr. 8 poz., sum. - 2 Ogólnopolskie Mikrosympozjum pt. Technologie hybrydyzacji DNA w diagnostyce zakażeń wirusem cytomegalii (HCMV) i innymi herpeswirusami Łódź 25.09. 2002
Sygnatura GBL: 304,786

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • pediatria
  • choroby zakaźne

    Typ dokumentu:
  • praca kliniczna
  • praca związana ze zjazdem

    Wskaźnik treści:
  • ludzie
  • noworodki
  • niemowlęta
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: We have analysed 16 children aged 3 weeks to 15 months, who were hospitalised in Department of Infectious Diseases, Medical University of Lodz with initial diagnosis of cytomegalovirus infection. Nine of them showed clinical symptoms of cytomegaly: interstitial pneumonia, hepatitis, neurological abnormalities. They were treated for three weeks with intravenous ganciclovir (Cymevene) 5 mg/kg, twice a day. The treatment was successful: pneumonia and hepatitis resolved but the drug had no influence on neurological symptoms. Seven other children were diagnosed with asymptomatic CMV infection and the resolved without specific antiviral treatment.


    2/5

    Tytuł oryginału: Antygeny zgodności tkankowej klasy II a odpowiedź na leczenie interferonem-ŕ2b przewlekłego zapalenia wątroby typu C.
    Tytuł angielski: HLA class II alleles and response to hepatitis C treatment with interferon-ŕ2b.
    Autorzy: Piekarska Anna, Woszczek Grzegorz, Sidorkiewicz Małgorzata, Kuydowicz Jan
    Źródło: Prz. Epidemiol. 2002: 56 (1) s.123-128, tab., bibliogr. 17 poz., sum.
    Sygnatura GBL: 301,250

    Hasła klasyfikacyjne GBL:
  • farmacja
  • immunologia
  • gastroenterologia

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie polskie: W pracy oceniono sugerowany związek między wybranymi allelami antygenów zgodności tkankowej-HLA klasy II a odpowiedzią na leczenie przewlekłego zaplenia wątroby typu C interferonem-ŕ2b.

    Streszczenie angielskie: Background/Aims. The mechanisms of humoral immunological response in chronic hepatitis C are not fully understood. It would be interesting to correlate HLA II alleles with the therapeutic response to interferon alfa2b treatment in patients with chronic hepatitis C. Such correlation has not yet been described. The purpose of the study was to correlate the presence of HLA alleles in chronic hepatitis C patients with results of interferon-alfa2b therapy. Methods. We assessed HCV-RNA presence in serum by RT-PCR and HLA-DR B*1/alleles by PCR-SSP for locus I and II in 54 patients with chronic hepatitis C. All patients were treated with interferon alfa2b for six month. Results of the therapy were evaluated 18 months after the end of treatment. Results. Based on the treatment results (TR - therapeutic response) patients were retrospectively qualified into three groups: sustained responders (SR) - 18.6 p.c. (10/54), relapsers (R) - 48.1 p.c. (26/54), non responders (NR) - 33.3 p.c. (18/54). Allele DRB1* 07 and allele DRB1* 13 were more frequent among patients in NR and TR group, respectively. Observed diffrences were not statistically significant (p 0.05). Conclusion. In the group of 54 adults with chronic hepatitis C no correlation between the presence of HLA-DRB1* alleles and response to interferon alfa2b therapy was found.


    3/5

    Tytuł oryginału: Trudności diagnostyczne w przypadku gruźliczego zapalenia opon mózgowo-rdzeniowych i mózgu.
    Tytuł angielski: Diagnostic problems in tuberculous meningoencephalitis.
    Autorzy: Piekarska Anna, Kuydowicz Jan
    Źródło: Pneumonol. Alergol. Pol. 2002: 70 (9/10) s.504-508, bibliogr. 15 poz., sum.
    Sygnatura GBL: 301,096

    Hasła klasyfikacyjne GBL:
  • neurologia

    Typ dokumentu:
  • praca kazuistyczna

    Wskaźnik treści:
  • ludzie
  • dorośli 45-64 r.ż.
  • płeć męska

    Streszczenie angielskie: Tuberculous meningoencephalitis (TBM) is a rarely diagnosed form of tuberculosis. It is characterised with high mortality. Only rapidly started treatment allows to patient's survival. However, bacteriologic prove of the diagnosis is achieved only in 40 p.c. of cases. It was hoped that introduction of PCR to clinical practice, would allow rapid and unquestionable diagnosis. We present case of male with lymphocytic bacterial meningoencephalitis in whom tuberculous etiology was suspected. The diagnosis was abandoned when negative results of PCR was obtained. As cessation of treatment led to dramatic worsening of patients state, the antituberculosis therapy was restarted. After 2 months of therapy, complete clinical remission was achieved. Nevertheless, computed tomography of brain revealed clinically asymptomatic hydrocephalus. Presented case shows that the treatment is effective, it should not be ended even in case of negative results of PCR test.


    4/5

    Tytuł oryginału: Czy oznaczanie stężeń białek ostrej fazy w płynie mózgowo-rdzeniowym lub/i w surowicy w wirusowym zapaleniu opon mózgowo-rdzeniowych u dzieci ma znaczenie diagnostyczne?
    Tytuł angielski: Does testing for acute phase proteins play a role in diagnosis of viral meningitis in children. P. 1: Limphocytic meningitis caused by parotitis epidemica.
    Autorzy: Łobos Marek, Rusinek Alicja, Paradowski Marek, Kuydowicz Jan, Stanisławska-Majda Ewa, Mamełka Beata, Szablewski Mariusz, Piątas Sławomir
    Źródło: Prz. Epidemiol. 2002: 56 (4) s.615-622, tab., bibliogr. 35 poz., sum.
    Sygnatura GBL: 301,250

    Hasła klasyfikacyjne GBL:
  • choroby zakaźne
  • pediatria
  • neurologia

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dzieci 2-5 r.ż.
  • dzieci 6-12 r.ż.
  • dzieci 13-18 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie polskie: Wykazano, że u dzieci z limfocytarnym zapaleniem opon mózgowo-rdzeniowych (zom) wywołanym w następstwie powikłań nagminnego zapalenia przyusznic, dochodzi do wywołania słabo zaznaczonej reakcji ostrej fazy i tym samym wzrostu stężeń wybranych białek ostrej fazy (bof) w płynie mózgowo-rdzeniowym (pmr) lub/i surowicy krwi. Określono przydatność oznaczeń bof w diagnozowaniu i monitorowaniu przebiegu tej choroby.

    Streszczenie angielskie: Objective: We examined whether an acute phase reaction could occur in children with lymphocytic meningitis of hemogeneous etiology (parotitis epidemica from the Paramyxoviridae family), a sign of which would be an inrease in concentrations of acute phase proteins (APP's) in cerebrospinal fluid (CSF) and/or in blood serum. We also tested the usefulness of the determination of selected APP's concentrations in CSF and serum in diagnosis and monitoring of the course of the disease, provided that an increase in concentrations of selected APP's were discernible. Methods: Cases were 78 children with lymphocytic meningitis as a complication of parotitis epidemica. Controls were 30 healthy children (control group K1) and 19 children hospitalized with suspected meningitis (control group K2). The following APP's presence in CSF and serum were tested: C-reactive protein (CRP0, alpha-2haptoglobin (HPT), alpha-1-antitripsin (AAT) and alpha-1-acid- glycoprotein (AAG), alpha-2-ceruloplasmin (CER) and alpha-2-macroglobin (AMG). The results were compared and analyzed. Results: The results of the research show a significant increase in all APP's determined, except for CRP and AAG, in children with parotidal meningitis. Conclusions: Determination of CRP concentration either in CSF or in serum is not useful in diagnosis of parotidal meningitis and in differentiation of lymphocytic and bacterial forms of the disease.


    5/5

    Tytuł oryginału: Prevalence of markers of hepatotropic viruses A, B, C and the efficacy of vaccination against hepatitis A and hepatitis B among medical students.
    Autorzy: Jabłkowski Maciej, Kuydowicz Jan, Strzelczyk Janusz, Białkowska Jolatna
    Źródło: Med. Sci. Monitor 2002: 8 (11) s.CR762-CR766, tab., bibliogr. 36 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • gastroenterologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: Hepatitis A and B can be prevented by active immunization. The purpose of our study was to estimate the prevalence of viral markers of hepatitis A, B, and C among medical students, to assess the efficacy of vaccination against HBV infection after 4 years, and to evaluate the efficacy of vaccination against HAV infection. Material/Methods: The study group consisted of 150 medical students, who were vaccianted with ENgerixtm B at the beginning of medical studies. From this population we identified a subgroup of 45 students, in whom the presence of anti-HAV was not confirmed; they were then vaccinated with HAVRIXtm 1440. Viral markers for HAV, HBV, HCV were determined in this group. Results: In the group of 150 persons, we found anti-HBc in 8 students (5.3 p.c.), and HBsAg in 1 (0.7 p.c.), who did not have either HBeAg or anti-HBe. Anti-HBs antibodies were found in 146 students (97.3 p.c.); anti-HCV in 3 cases (2 p.c.), and anti-HAV in 15 cases (10 p.c.). After 2-fold vaccination against viral hepatitis A, 100 p.c. of the students presented with anti-HAV. Conclusion: The incidence of HBsAg and anti-HCV among our students is the same as in the general population, while the incidence of anti-HAV is much lower (10 p.c.). The presence of anti-HBs 4years after vaccination was detected in 97.3 p.c. of the students, and anti-HAV 1 month after the complete course of vaccination in 100 p.c. of cases.

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