Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL
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KRZANOWSKI
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Tytuł oryginału:
International Journal of Cardiology
Tytuł angielski:
Verapamil improves the pacing-induced vasodilatation in symptomatic patients with hypertrophic cardiomyopathy.
Autorzy:
Dimitrow
Paweł Petkow,
Krzanowski
Marek,
Grodecki
Janusz,
Małecka
Barbara,
Lelakowski
Jacek,
Kawecka-Jaszcz
Kalina,
Szczeklik
Andrzej,
Dubiel
Jacek S.
Źródło:
Int. J. Cardiol. 2002: 83 (3) s.239-247, tab., bibliogr. 52 poz.
Sygnatura GBL:
305,693
Hasła klasyfikacyjne GBL:
farmacja
kardiologia
Typ dokumentu:
praca kliniczna
praca opublikowana za granicą
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
Streszczenie angielskie:
The purpose of the study was to assess the effect of varapamil on the response of diastolic coronary flow velocity and coronary vascular resistance to pacing in symptomatic patients with hypertrophic cardiomyopathy. In 14 patients with hypertrophic cardiomyopathy, the coronary flow velocity was detected in the left anterior descending coronary artery using transthoracic Doppler echocardiography. The peak diastolic coronary flow velocity and coronary and coronary vascular resistance was measured at baseline and during pacing. Changes of these parameters induced by the pacing (expressed as the percentage of baseline values) were compared on varapamil treatment and after verapamil withdrawal. The same measurements were obtained in ten control subjects. The results show that, in hypertrophic cardiomyopathy patients, increase in coronary flow velocity during pacing was significantly higher on than off varapamil therapy (64.8 ń 32.5 vs. 41.1 ń 21.3 p.c., P 0.05). In control subjects, pacing-induced increase in coronary flow velocity was comparable to changes in coronary flow velocity in hypertrophic cardiomyopathy patients receiving verapamil (80.2 ń 18.4 vs. 64.8 ń 32.5 p.c., P 0.05). After verapamil withdrawal in hypertrophic cardiomyopathy patients, coronary flow velocity increase during pacing was significantly lower than in control subjects (41.1 ń 21.3 vs. 80.2 ń 18.4 p.c., P 0.05). During pacing the coronary vascular resistance decreased more on verapamil than after drug withdrawal (-34.7 ń 11.7 vs. -24.6 ń 12.9 p.c., P 0.05). In control subjects the coronary...
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Tytuł oryginału:
Diagnostyka ultrasonograficzna zwężenia początkowego odcinka tętnicy kręgowej.
Tytuł angielski:
Ultrasound diagnosis of vertebral artery ostial stenosis.
Autorzy:
Krzanowski
Marek,
Bodzoń
Wojciech,
Wandzilak
Maciej
Źródło:
Pol. J. Radiol. 2002: 67 (4) s.21-25, il., bibliogr. 10 poz., sum.
Sygnatura GBL:
301,279
Hasła klasyfikacyjne GBL:
kardiologia
radiologia
Typ dokumentu:
praca kliniczna
Wskaźnik treści:
ludzie
dorośli 19-44 r.ż.
dorośli 45-64 r.ż.
dorośli = 65 r.ż.
płeć męska
płeć żeńska
Streszczenie angielskie:
The purpose of the study was to assess the value of a Doppler ultrasound in the diagnosis of vertebral artery ostial stenosis in a prospective study verified by arteriography. A ratio of end diastolic velocities within ostium and V2 segment of vertebral artery above 1.5 was considered abnormal, indicative for a significant (i.e. 50 p.c. diameter) stenosis. 52 patients (24 women, age 58 ń 10.7) scheduled for a two-dimensional aortic arch arteriography were studied. There were 25 significant vertebral artery ostial stenoses and 6 occulsions on arteriography. Sensitvity, specificity, positive and negative predictive values for Doppler ultrasound were 100 p.c., 93 p.c., 86 p.c. and 100 p.c., respectively. Out of 4 false-positive cases, in 3 the artery was hypoplstic and there was a concommittant significant extracranial artery occlusive disease. All 7 cases of subclavian steal (2 ostial stenoses) and 3 cases of occlusions were correctly diagnosed. In 7 cases the artery couuld not be assessed by ultrasound - in this group there were 3 occlusions and 1 patient, but hypoplastic artery originating from the aortic arch. End-diastolic velocity ration provides an accurate means of the vertebral artery ostial stenosis detection. It can be assessed in almost all cases and gives reliable results even in the presence of subclavian steal. It's value in cases of hypoplastic vertebral arteries remains to be determined. The role of Doppler ultrasound in vertebral artery occlusion diagnostics is limited.
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