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Tytuł oryginału: Izmenchivost mitokhondrialnojj DNK v populaciakh russkovo naselenia Stavropolskovo kraja, Orlovskojj i Saratovskojj oblastejj.
Tytuł angielski: Mitochondrial DNA variation in Russian populations of Stavropol Krai, Oreal and Saratov Oblasts.
Autorzy: Malyarchuk B. A., Derenko M. V., Grzybowski T., Czarny J., Miścicka-Śliwka D[anuta], Denisova G. A., Kostyunina E. A.
Źródło: Genetika 2002: 38 (11) s.1532-1538, tab., bibliogr. 29 poz., sum.
Sygnatura GBL: 304,994

Hasła klasyfikacyjne GBL:
  • genetyka

    Typ dokumentu:
  • praca epidemiologiczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Mitochondrial DNA (mtDNA) polymorphism was examined in three Russian populations from the European part of Russia (Stavropol krai, Oreel oblast, and Saratov oblast). This analysis showed that mitochondrial gene pool of Russians was represented by the mtDNA types belonging to haplogroups H, V, HV*, J, T, U, K, I, W and X. A mongoloid admixture (1.5 p.c.) was revealed in the form of mtDNA types of macrophaplogroup M. Comparative analysis of the mtDNA haplogroup frequency distribution patterns in six Russian populations from the European part of Russia indicated the absence of substantial genetic differences between them. However, in Russian populations from the southerm and central region the frequency of haplogroup V (average frequency 8 p.c.) was higher than in the populations from more northern regions. Based on the data on mtDNA HVS1 sequence variation, it was shown that the diversity of haplogroup V in Russians (h = 0.72) corresponded to the highest h values observed in Europe. The reasons for genetic differention of the Russian population (historical, ecological, and adaptative) are discussed.

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