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Tytuł oryginału: MyHC II content in the vastus lateralis m. quadricipitis femoris is positively correlated with the magnitude of the non-linear increase in the VO2/power output relationship in humans.
Autorzy: Żołądź J[erzy] A., Duda K., Karasiński J., Majerczak J., Kołodziejski L., Korzeniewski B.
Źródło: J. Physiol. Pharmacol. 2002: 53 (4 p. 2) s.805-821, il., tab., bibliogr. 33 poz.
Sygnatura GBL: 302,092

Typ dokumentu:
  • praca kliniczna
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska

    Streszczenie angielskie: In the study we have examined the relationship between the content of different isoforms of MyHC in the vastus lateralis. m. quadricipitis femoris and the VO2/power output relationship during incremental cycling exercise. Twenty-one male subjects: aged 24.0 ń 2.5 years, body mass 73.0 ń 7.2 kg, height 179 ń 5 cm, BMI 22.78 ń 1.84 kg ú m-2, VO2max 3697 ń 390 ml ú min-1, 50.9 ń 5.2 ml ú kg-1 ú min-1, participated in this experiment. The subjects performed an incremental exercise test unit exhaustion. The wxercise test started at power output of 30 W, followed by an increase amounting to 30 W every 3 minutes. The pedalling rate was maintained at 60 rev min-1. Gas exchange variables were measured continuously using breath-by-breath system Oxycon Jaeger. At the end of each step blood samples were taken for lactate concentration. Muscle biopsy samples taken from the vastus lateralis m. quadricipitis femoris, using the Bergstrom needle, were analysed for the content of different MyHC (I, IIa, IIx) using SDS-PAGE and Western blotting. The pre-exercise VO2, as a mean value of six-minute measurements, expressed both in min-1, and in ml ú kg-1 ú min-1, was positively correlated with the content of MyHC II in the vastus lateralis (p 0.01). We have also found that the pre-exercise values of VO2 in the group of subjects with a high proportion of MyHC II (59.9 ń 11.2 p.c.) were significantly higher (p 0.02, when VO2, was expressed in ml ú min-1, and p 0.01 when VO2 was expressed in ml ú kg-1 ú min-1) than in the group with low content of MyHC II (27.5 ń 6.0 p.c.) in the vastus...

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