Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: KORPANTY
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Wpływ histaminy oraz leków przeciwhistaminowych drugiej generacji na układ krążenia.
Tytuł angielski: The influence of histamine and second generation of antihistamine drugs on cardiovascular system.
Autorzy: Adamek-Guzik Teresa, Korpanty Grzegorz, Guzik Tomasz, Czerniawska-Mysik Grażyna
Źródło: Pol. Arch. Med. Wewn. 2002: 108 (2) s.785-795, il., tab., bibliogr. 45 poz.
Sygnatura GBL: 313,501

Hasła klasyfikacyjne GBL:
  • toksykologia
  • immunologia
  • kardiologia

    Wskaźnik treści:
  • ludzie

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    Tytuł oryginału: Urinary leukotriene levels are increased during exacerebation of atopic eczema/dermatitis syndrome. Relation to clinical status.
    Autorzy: Adamek-Guzik T., Guzik T. J., Czerniawska-Mysik G., Korpanty G., Mastalerz L., Radwan J., Szczeklik A.
    Źródło: Allergy 2002: 57 (8) s.732-736, il., tab., bibliogr. 24 poz.
    Sygnatura GBL: 302,302

    Hasła klasyfikacyjne GBL:
  • dermatologia i wenerologia

    Typ dokumentu:
  • praca kliniczna
  • praca opublikowana za granicą
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dzieci 13-18 r.ż.
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: Leukotrienes are potent mediators of allergic inflammation and their role in the pathogenesis of allergic disorders, particularly asthma, is well established. Their importance in the pathogenesis of atopic eczema/dermatitis syndrome (AEDS) is still unclear. We aimed to compare urinary cysteinyl leukotriene (Cys-LT) levels during exacerbation and remission of AEDS in relation to clinical status, IgE levels, and eosinophil counts. Methods: Urinary Cys-LTs were measured by direct enzyme immunoassay in 17 adult patients with AEDS and in 17 healthy controls in whom atopy had been excluded. Cys-LTs were compared during exacerbation and remission of AEDS in relation to the clinical status measured by SCORAD. Total IgE levels were measured by enzyme-linked immunoassay (ELISA). Results: Mean clinical score during the exacerbation was 64.3 ń 3.1 and during remission 22.4 ń 4 (P 0.01). Cys-LTs were significantly higher during the exacerbation of AEDS than in the control group (230.9 ń 20.8 vs 123.2 ń 9.9 pg/mg creatinine; P 0.005). During the remission, the difference between AEDS patients and the control group was not significant (96.3 ń 8.7 vs 123.2 ń 9.9 pg/mg creatinine; P = 0.8). During AEDS exacerbation Cys-LTs levels were significantly correlated with the clinical status (rs = 0.73, P 0.01) and with eosinophil counts (r = 0.86; P 0.01) but not with the duration of the disease, age of patients, or IgE levels. Conclusions: Our results point to enhanced biosynthesis of Cys-LTs during the AEDS exacerbations. Inflammatory cells, e.g. eosinophilis are the most...

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