Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Lekooporność gronkowców izolowanych od chorych leczonych ambulatoryjnie.
Tytuł angielski: Susceptibility to antibiotics, occurrence of methicillin-resistant strains and production of á-lactamases by Staphylococci isolated from outpatients.
Autorzy: Chylak Jerzy, Kopka Anita
Źródło: Med. Dośw. 2002: 54 (2) s.97-101, tab., bibliogr. 9 poz., sum.
Sygnatura GBL: 301,458

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • farmacja

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie

    Streszczenie polskie: Określono lekooporność szczepów gronkowców izolowanych w latach 1999-2000 od chorych leczonych ambulatoryjnie z terenu miasta Poznania. Określono też częstość występowania gronkowców metycylinoopornych, oraz zdolność wytwarzania laktamaz.

    Streszczenie angielskie: The aim of the study was to determine susceptibility of 587 strains of S. aureus and 85 strains of coagulase - negative staphylococci isolated from outpatients in Poznań to co-trimoxazole, amoxycillin/clavulanic acid, erythromycin, gentamycin, doxycycline, ampicillin, oxacillin, cephradine, clindamycin and neomycin. Also methicillin-resistant strains were determined as well as strains ability to produce lactamases. Susceptibility testing and examination of methicillin-resistant strains were performed by the disc diffusion techniques according to recommendation of NCCLS. Methicillin-resistant strains were additionally examined to their sensitivity to vankomycin and teicoplanin. á-lactamase production was detected using nitrocefin impregnated disc and iodometric method. Amoxacillin/clavulanic acid, gentamycin, co-trimoxazole, cephradin, oxacillin and clindamycin occurred to be very active both, S. aureus and coagulase-negative staphylococci. 84.7 p.c. to 100 p.c. of examined strains were sensitive to these drugs. Doxycyclin, erythromycin and ampicillin were less effective. Nine strains (1.5 p.c.) of 587 strains of S. aureus as well as 7 strains (8.7 p.c.) of coagulase-negative staphylococci were methicillin-resistant. All of methioocillin-resistant strains were sensitive to vancomycin and teicoplanin. More than 75 p.c. of S. aureus and close to 50 p.c. of coagulase-negative staphylococci were able to produce á-lactamases.

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