Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: KLATT
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Tytuł oryginału: Częstość występowania gruźlicy lekoopornej w Polsce w 2000 r. w porównaniu z 1997 r.
Tytuł angielski: Frequency of drug resistant tuberculosis in Poland in 2000 in comparison to 1997.
Autorzy: Augustynowicz-Kopeć Ewa, Zwolska Zofia, Jaworski Albert, Kostrzewa Elżbieta, Klatt Magdalena, Świderska Agnieszka, Drozd Irena
Źródło: Pneumonol. Alergol. Pol. 2002: 70 (3/4) s.193-202, il., tab., bibliogr. 15 poz., sum.
Sygnatura GBL: 301,096

Hasła klasyfikacyjne GBL:
  • pulmonologia

    Typ dokumentu:
  • badanie porównawcze
  • praca epidemiologiczna

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Prevalence of drug resistance to one drug and multidrug resistance - MDR in different categories of tuberculosis patients is an important information about the susceptibility pattern of Mycobacterium tuberculosis isolates against antimycobacterial drugs. Poland joined WHO/IUATLD global project on TB drug resistance surveillance, and carried out in 1996/1997 the first prospective survey, simultaneously on primary and acquired drug resistance. This study is repeated in 2000 according to the WHO/IUATLD protocol. The programme covered the whole country. A total of 16 regional centers participated in the co-operative study. 3705 questionnaires and cultures were obtained from patients who excreated TB bacilli during the 12-months from 1 st. january to 31 st. december 2000. Drug resistance tests to INH, RMP, SM, EMB were performed on lowenstein-Jensen medium according to the proportion method or/and Bactec 460 TB system. 3705 TB patients (3037 new and 668 treated cases) bacteriologically confirmed by culture were included in one-year study. Primary resistance to any drug was found in 6,21 p.c. (Cl 5,27 - 6,56) of new cases. 35 patients (1,15 p.c., Cl 0,77 - 1,35) were infected with MDR strains. Acquired resistance to and drug was found in 16,6 p.c. (Cl 5,27 - 6,56), 8,53 p.c. (Cl 6,41 - 9,6) of the patients who excreated MDR strains. We have increased resistance from 3,6 p.c. in 1997 to 6,12 p.c. (p 0,001) in 2000 and MDR from 0,6 p.c. in 1997 to 1,15 p.c. (p 0,001) in 2000 in untreated tuberculosis patients in Poland. The rate of resistance in the group of treated TB patients...


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    Tytuł oryginału: Czułość metody bakterioskopowej w wykrywaniu prątków gruźlicy i MOTT na podstawie analizy 22.218 badań diagnostycznych przeprowadzonych w zakładzie mikrobiologii IGiCHP w okresie 1998 - 2001.
    Tytuł angielski: Sensitivity of microscopy for detection of Mycobacterium tuberculosis and MOTT (Mycobacteria other than tuberculosis) on the basis of analysis 22.218 clinical materials submitted in 1998-2001 to Department of Microbiology in National Tuberculois and Lung Diseases Research Institute in Warsaw, Poland.
    Autorzy: Zwolska Zofia, Augustynowicz-Kopeć Ewa, Kostrzewa Elżbieta, Świderska Agnieszka, Klatt Magdalena, Jaworski Albert
    Źródło: Pneumonol. Alergol. Pol. 2002: 70 (7/8) s.368-377, tab., bibliogr. 30 poz., sum.
    Sygnatura GBL: 301,096

    Hasła klasyfikacyjne GBL:
  • choroby zakaźne
  • mikrobiologia
  • pulmonologia

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: The results of 22.218 respiratory specimens sent to our laboratory were studied to determine the sensitivity of the Ziehl-Neelsen (Z-N) stain and microscopy - fluorescence method for detection of M.tbc and MOTT. There were no AIDS patients among analyzed casees. Smears were positive for acid fast bacilli (AFB) 60,0 p.c. (480 of 800) of specimens growing M. tuberculosis and 25,1 p.c. (219 of 872) of specimens growing the six common species of MOTT. Smear positivity by species was 28,1 p.c. (141 of 502) for M. kansasii, 29,4 p.c. (43 of 146) for MAIC, 28,7 p.c. (35 of 122) for M. xenopi. No smear was positive for M. gordone (43 cultures), M. fortuitum (33 cultures), M. scrofulaceum (26 cultures). The rate of nonculturable mycobacteria on L-J medium was 0,2 p.c., mean rate of contamination was 4,6 p.c. We also analyzed the relation betweenthe number of AFB seen on the smear and time of the growth of M. tuberculosis and relation between abundance of the culture growth and AFB seen on smears. These study suggest that the sensitivity of microscopy for Mycobacterium tuberculosis is comparable with the data of others authors. Sensitivity of microscopy is lower in MOTT detection than for M.tbc (p 0,001). Time of growth and abundance of the M. tuberculosis cultures were adequate to AFB seen in microscopy.

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