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Tytuł oryginału: Comparison of the bladder tumour antigen test with photodynamic diagnosis in patients with pathologically confirmed recurrent superficial urinary bladder tumours.
Autorzy: Lipiński M., Jeromin L.
Źródło: Br. J. Urol. 2002: 89 (7) s.757-759, bibliogr. 20 poz.
Sygnatura GBL: 300,816

Hasła klasyfikacyjne GBL:
  • onkologia
  • urologia

    Typ dokumentu:
  • praca kliniczna
  • praca opublikowana za granicą
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Objective: To verify the sensitivity of the bladder tumour antigen (BTAstat, Bard Urological, Convington, GA) test against the sensitive procedure of photodynamic diagnosis (PDD), in which 5-aminolaevulinic acid (5-ALA, a precursor of fluorescent porphyrins) is absorbed by the tumour and detected by ultraviolet cystoscopy, in the early diagnosis of urinary bladder tumours. Patients and methods: Forty-three patients (31 men and 12 women, age range 21-87 years) were assessed after transurethral resection of their bladder tumour using the BTAstat test and PDD. Sixty-nine biopsies from suspect areas of bladder mucosa were taken during cystoscopy under ultraviolet light and all suspect lesions electrocoagulated. Results: Thirty-five patients (81 p.c.) had a positive BTAstat test; in these patients PDD detected malignant lesions (17 Ta1G1-2, two T1G2, two T1G3 and 14 Tis). In eight patients (19 p.c.) the BTAstat was negative but PDD detected three malignant lesions (two Tis and one TaG1). Conclusions: PDD is valuable for detecting bladder malignancy and can identify small lesions not detected by the BTAstat test.

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