Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: JAHNOVA
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Assessment of biomarkers of the immunomodulatory effects of asbestos in asbestos cement plant workers.
Autorzy: Tulinska Jana, Dusinska Maria, Jahnova Eva, Liskova Aurelia, Kuricova Miroslava, Weissova Silvia, Horvathova Mira, Wsolova Ladislava, Machata Miroslaw, Kyrtopoulos Soterios A., Fuortes Laurence
Źródło: Prz. Epidemiol. 2002: 56 supl.: Conference on molecular epidemiology in preventive medicine - achievements and new challenges s.95-101, il. - Konferencja pt. Molekularna epidemiologia w medycynie prewencyjnej - osiągnięcia i nowe wyzwania Kraków 20-22.06. 2002
Sygnatura GBL: 301,250

Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • toksykologia
  • immunologia

    Typ dokumentu:
  • praca związana ze zjazdem
  • tytuł obcojęzyczny
  • praca epidemiologiczna

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Immune parameters were examined in 61 workers exposed to asbestos fibres for an average of 23 years as well as in 46 town and 21 in-factory unexposed controls. Humoral immunity was evaluated by levels of immunoglobulins, concentrations of interleukins and soluble adhesion molecules. Cellular immunity was determined by phenotypic analysis of peripheral blood leukocytes (CD3, HLA DR, CD4, CD8, CD16+56, CD19), expression of adhesion molecules on leukocytes and activation markers on eosinophils. Immune function assays - proliferative response of lymphocytes and phagocytic activity of leukocytes were evaluated in exposed and unexposed populations. Using multifactorial analysis of variance we found significantly increased levels of immunoglobulin E, concentrations of IL-6 and soluble adhesion molecule ICAM-1 in asbestos exposed workers. Expression of adhesion molecule CD62L (L-selectin) on monocytes and granulocytes was significantly higher in explosed workers. Moreover CD69 and CD66b markers on eosinophils were significantly increased among people exposed to asbestos. Immune function assays showed a significant decrease in proliferative response of lymphocytes stimulated by T-cell mitogen PHA in the exposed group. Proliferation of lymphocytes stimulated through T-cell receptors, T-dependent B-cell response an memory cell function did not differ between exposed workers and controls. Spearman correlation analysis revealed decreasing proliferative response of T and B-lymphocytes in the exposed population with ...

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    Tytuł oryginału: Hyperacute rejection of living related kidney graft caused by IgG endothelial specific antibodies with a negative monocyte cross-match.
    Autorzy: Grandtnerova Barbara, Laca L'udovit, Jahnova Eva, Horvathova Miroslava, Balaz Vladimir, Hovoricova Blanka, Hudec Peter, Zarnovicanova Maria
    Źródło: Ann. Transplant. 2002: 7 (4) s.52-54, bibliogr. 27 poz.
    Sygnatura GBL: 313,259

    Hasła klasyfikacyjne GBL:
  • immunologia
  • nefrologia
  • transplantologia

    Typ dokumentu:
  • praca kazuistyczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska

    Streszczenie angielskie: We present a case report of a 30-year-old man, who hyperacutely rejected a blood group identical. HLA-haploidentical living related kidney graft in spite of the fact that he had never been immunized. Anti-endothelial IgG antibodies that did not react with monocytes were detected with flow cytometry, on a panel of human umbilical cord cells in his serum retrospectively. On the basis of this exeperience we put for consideration the possibility of regular examination of non-HLA antibodies in potential living graft recipients.

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