Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Rola regulacji ekspresji genów w stabilności plazmidów.
Tytuł angielski: The role of regulation of gene expression in plasmid stability.
Autorzy: Jagura-Burdzy Grażyna
Źródło: Kosmos 2002: 51 (3) s.319-330, il., bibliogr. [32] poz., sum.
Sygnatura GBL: 313,370

Hasła klasyfikacyjne GBL:
  • genetyka

    Streszczenie angielskie: Plasmid survival relies heavily on the regulation of gene expression assuring the balance between the necessity of a certain level of plasmid genetic information being expressed and minimalization of the metabolic burden imposed on the host. The most commonly used regulatory mechanisms are autogenous repression and antisense RNA-mRNA interactions which provide the systems with economy, simplicity, sensitivity and possibility of rapid response to internal and external changes. IncP-1 plasmids are described in more detail as the paradigm of a multivalent regultory network, responsible for tight repression, coordination and fine-tuning of almost all plasmid functions and providing simultaneously a high level of security to plasmid genome. Appropriate recognition and use of environmental stimuli as very important factors in plasmid biology is nicely exhibited by Ti plasmids of Agrobacterium tumefaciens and phermone-responsive plasmids of Enterococcus feacalis.

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