Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: JABŁKOWSKI
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Wpływ IGF-I oraz IGFBP-3 na gęstość mineralną kości u kobiet z przewlekłymi chorobami wątroby.
Tytuł angielski: Effects of IGF-I and IGFBP-3 on bone mineral density in women with chronic liver diseases.
Autorzy: Skowrońska-Jóźwiak Elżbieta, Białkowska Jolanta, Jabłkowski Maciej, Lewiński Andrzej
Źródło: Terapia 2002: 10 (6) s.35-36, bibliogr. 9 poz., sum.
Sygnatura GBL: 313,048

Hasła klasyfikacyjne GBL:
  • gastroenterologia
  • traumatologia i ortopedia

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • płeć żeńska

    Streszczenie angielskie: The progressing decrease of IGF-I concentration in serum may be one of the factors, particpating in the pathogenesis of osteoporosis. IGFBP-3 is a IGF-I-binding protein, standing for a metabolic reservoire of IGF-I and prolonging the half-life time of the latter. In the course of chronic liver diseases, protein synthesis is suppressed. The goal of the study was to assess the effects of IGF-I and IGFBP-3 on bone mineral density (BMD) in premenopausal women with chronic liver diseases. Results: The mean concentration of IGF-I in the studied group was 185.3 (8.8 ng/mL, manifesting a positive correlation with BMD (r=0.5, p 0.05). The mean concentration of IGFBP-3 was 2161 (14.1 ng/mL, correlating with BMD (r = 0.52, p 0.04). In seven (7) patietns (43.8 p.c.), BMD was decreased and the concentrations of IGF-I and IGFBP-3 were significantly lower (p 0.05). Conclusion: Our observations indicate that patietns with chronic liver diseases are at particular risk of secondary osteoporosis, the decreased concentrations of IGF-I and IGFBP-3 being probably involved in this process.

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    Tytuł oryginału: Prevalence of markers of hepatotropic viruses A, B, C and the efficacy of vaccination against hepatitis A and hepatitis B among medical students.
    Autorzy: Jabłkowski Maciej, Kuydowicz Jan, Strzelczyk Janusz, Białkowska Jolatna
    Źródło: Med. Sci. Monitor 2002: 8 (11) s.CR762-CR766, tab., bibliogr. 36 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • gastroenterologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: Hepatitis A and B can be prevented by active immunization. The purpose of our study was to estimate the prevalence of viral markers of hepatitis A, B, and C among medical students, to assess the efficacy of vaccination against HBV infection after 4 years, and to evaluate the efficacy of vaccination against HAV infection. Material/Methods: The study group consisted of 150 medical students, who were vaccianted with ENgerixtm B at the beginning of medical studies. From this population we identified a subgroup of 45 students, in whom the presence of anti-HAV was not confirmed; they were then vaccinated with HAVRIXtm 1440. Viral markers for HAV, HBV, HCV were determined in this group. Results: In the group of 150 persons, we found anti-HBc in 8 students (5.3 p.c.), and HBsAg in 1 (0.7 p.c.), who did not have either HBeAg or anti-HBe. Anti-HBs antibodies were found in 146 students (97.3 p.c.); anti-HCV in 3 cases (2 p.c.), and anti-HAV in 15 cases (10 p.c.). After 2-fold vaccination against viral hepatitis A, 100 p.c. of the students presented with anti-HAV. Conclusion: The incidence of HBsAg and anti-HCV among our students is the same as in the general population, while the incidence of anti-HAV is much lower (10 p.c.). The presence of anti-HBs 4years after vaccination was detected in 97.3 p.c. of the students, and anti-HAV 1 month after the complete course of vaccination in 100 p.c. of cases.

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