Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: The effect of altered fractionation schedule on the spinal cord response: radiobiological considerations.
Autorzy: Supe Sanjay S., Ganesh K. M., Velmurugan J., Rana B. S., Sankar B. N.
Źródło: Rep. Pract. Oncol. Radiother. 2002: 7 (1) s.27-35, tab., bibliogr. 18 poz.
Sygnatura GBL: 313,406

Hasła klasyfikacyjne GBL:
  • radiologia
  • neurologia

    Typ dokumentu:
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • zwierzęta

    Streszczenie angielskie: Increased fractionation spares late reacting normal tissued more than acute reacting normal tissues. A linear quadratic model is valid from large dose per fraction down to dose per fraction of 2 Gy. Experimental studies on animals and clinical studies on the spinal cord tolerance have shown incidences of myelopathy at doses lower than 50 Gy. The ŕ/á value of the linear quadratic model have been lower for low doses per fraction, indicating a sparing effect of altered fractionation for spinal cord myelitis. Animal data, clinical and radiobiological xplanations suggest of the radiobiological models. Further data suggest that one must not assume the spinal cord to have a greater tolerance at doses per fraction below the conventional dose per fraction of 2 Gy.

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    Tytuł oryginału: Radiobiological considerations of re-irradiation tolerance of the spinal cord.
    Autorzy: Supe Sanjay S., Ganesh K. M., Velmurugan J., Rana B. S., Sankar B. N.
    Źródło: Rep. Pract. Oncol. Radiother. 2002: 7 (2) s.81-85, tab., bibliogr. 12 poz.
    Sygnatura GBL: 313,406

    Hasła klasyfikacyjne GBL:
  • radiologia
  • neurologia

    Typ dokumentu:
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Re-irradiation tolerance of the spinal cord depends upon the volume of the spinal cord irradiated, the total dose, the dose per fractional, the elapssed time between the treatment and the region of the spinal cord involved. Clinical data on the treatment tolerance of the spinal cord are sparse and inconclusive. Radiobiological laboratory evidence has indicated the presence of long term recovery of the spinal cord damage. Fractionation sensitivity during reirradiation is comparable with the first session of radiation treatment. After an initial dose of 45 Gy, 50 p.c. recovery reported by Schulthesis and Stephens for an elapsed period of two years for re-irradiation considerations.

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