Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: FALLAH
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Eradication of Helicobacter pylori in duodenal ulcer disease Tetracycline & Furazolidone vs. Metronidazole & Amoxicillin in Omeprazole based triple therapy.
Autorzy: Mansour-Ghanaei Fariborz, Fallah Mohammad S., Shafaghi Afshin
Źródło: Med. Sci. Monitor 2002: 8 (3) s.PI27-PI30, tab., bibliogr. 37 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • gastroenterologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny
  • badanie porównawcze

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Background: The object of the study was to study the efficacy and safety of furazolidone and tetracycline compared to metronidazole an damoxicillin in an omeprazole based triple therapy in a prospective randomized-blind-clinical trial. Material/Methods: Patients with endoscopicaly verified active duodenal ulcer disease in the presence of Helicobacter pylori infection were eligible to enter the study. Endoscopy was performed a day before and 6-8 weeks after the cessation of treatment. H. pylori status was assessed by histologic examination (Giemsa stain) of biopsy specimens were taken from the antrum and corpus. H. pylori eradication was defined as absence in histology of the biopsy specimens at the second endoscopy. Ulcer healing was considered as decrease in ulcer size to less than 20 p.c. of its primary sieze. Patients were randomly assigned to receive omeprazole 20 mg, amoxicillin 1000 mg and metronidazole 500 mg (OAM group) or omeprazole 20 mg, tetracycline 500 mg and furazolidone 200 mg (OTF group). All medications were taken twice daily, for 2 weeks. Results: Out of 111 patients enrolled in the study, 108 completed a course of treatment and underwent a follow-up endoscopy, with 54 patients in each group. H. pylori eradication was achieved in 52 patients (96.3 p.c. - 95 p.c. CI: 91.27 - 100) in OTF gorup and 45 patietns (83.3 p.c. - 95 p.c. CI: 73.35 - 93.25) in OAM group (P = 0.015). Our study showed the superiority of OTF vs. OAM regimen with a 13 p.c. increment in eradication rate, with only occasional severe side effect. Conclusions: In conclusion OTF regiment is a safe, cheaper and effective alternative for OTF regimen and we recommend it to be used especially in developing countries.

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    Tytuł oryginału: Prevalence of hepatitis B and C seromarkers and abnormal liver function tests among hemophiliacs in Guilan (northern province of Iran).
    Autorzy: Mansour-Ghanaei Fariborz, Fallah Mohammad-Sadegh, Shafaghi Afshin, Yousefi-Mashhoor Mahmood, Ramezani Naghi, Farzaneh Farshid, Nassiri Reza
    Źródło: Med. Sci. Monitor 2002: 8 (12) s.CR797-CR800, il., tab., bibliogr. 23 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • pediatria
  • immunologia
  • mikrobiologia
  • hematologia

    Typ dokumentu:
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dzieci 2-5 r.ż.
  • dzieci 6-12 r.ż.
  • dzieci 13-18 r.ż.
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: The aim of the study was to determine the seroprevalence of hepatitis B and C viruses and abnormal liver function tests among hemophiliacs in Guilan province, Iran. Material/Methods: Patients registered with Guillan Hemophilia Society (GHS) were enrolled in this study, and evaluated for the presence of hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (HCV-Ab) and liver function tests. Results: One hundred and one patients (100 males, 1 female aged 19.7 years) from 110 registered hemophiliacs were enrolled in this study. 29 patients (28.7 p.c.) had elevated Alanine aminotransferase (ALT), 27 (26.7 p.c.) and 72 (71.3 p.c.) were positive for HBsAg and HCV-Ab, respectively. Seropositively for HCV-Ab correlated with the duration of treatment with clotting factor until 1997 (P = 0.01). There was also an inverse correlation between factor VIII and IX activity and seroporistively for HCV-Ab (P 0.001) and HBsAg (P 0.04). HCV-Ab was more likely to be positive among those received lyophilized factor VIII and cyroprecitate than hyophilazed factor VIII alone (P 0.01). In addition HCV-Ab seropositively was more commong among those received factor IX concentrate and fresh frozen plasma (FFP) than those received only FEP (P 0.01). Conclusion: Based upon our finding, prevalence of HBsAg positive cases in Guilan province was higher than other studies. Altough frequency of HCV-Ab was similar to other studies, frequency of increases ALT was less. Upon the results emerged from this study, we recommended that all hemophiliacs should be vaccinated against HBV...

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