Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: DIAZ-CASTELLANOS
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Clinical implications of acute mycoardial infarction complicated by high grade atrioventricular block.
Autorzy: Ruiz-Bail‚n Manuel, Hoyos Eduardo Aguayo de, Issa-Khozouz Ziad, Diaz-Castellanos Miguel Angel, López-Martinez Asunción, Calatrava-López Jes—s, Barranco-Ruiz Mercedes, Ruiz-Ferrón Francisco, Muńoz-Beltran Humberto Jos‚
Źródło: Med. Sci. Monitor 2002: 8 (3) s.CR138-CR147, tab., bibliogr. 35 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • kardiologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: The purpose of this study was to assess the incidence, clinical course, prognosis and mean length of stay in acute myocardial infarction (AMI) complicated by high-grade atrioventricular block (HAVB). Material/Methods: A retrospective cohort study including all AMI patietns listed from january 1995 to September 2000 in the ARIAM multi-center register. Univariate analysis was carried out to study the factors associated with the development of HAVB, the mortality ratek, and the mean length of stay, and multivariate logistic regression analysis to study whether HAVB is an independent predictive variable for mortality or prolongation of stay. Results: Of the 14.181 AMI patients included int he register, 837 (5.9 p.c.) presented with HAVB, which was associated with age, female sex, increased severity, diabetes, inferior and Q-wave AMIs, and a higher peak creatine phosphokinase (CPK) level. The HAVB patietns developed more complications, required more diagnostic-therapeutic resources, and showed significantly higher mortality (p 0.0001) and increased mean length of stay (p 0.0001). The independent risk factors for HAVB were age, maximum peak CPK, inferior or combined localization of the AMI, Q-wave AMI, diabetes, a Killip and Kimbal score 1, and thrombolysis. HAVB was found to be an independent predictive vairable for mortality and increased mean length of stay. Conclusions: AMI patients with HAVB, despite thrombolytic treatment, are at risk for complications, amortality and longer mean admissions. Further study is needed on the outcome of a more active reperfusion policy, such as direct, rescue angioplasty etc.


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    Tytuł oryginału: Alteplase: double bolus versus accelerated regimen.
    Autorzy: Ruiz-Bailen Manuel, Hoyos Eduardo Aguayo de, Hurtado-Ruiz Benjamin, Reina-Toral Antonio, Diaz-Castellanos Miguel Angel, Issa-Khozouz Ziad
    Źródło: Med. Sci. Monitor 2002: 8 (10) s.PI85-PI92, il., tab., bibliogr. 30 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • farmacja
  • kardiologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Background: The purpose of our study was to compare the efficacy and safety fo alteplase in acute myocardial infarction (AMI), when administered in a double bolus regimen or an accelerated regiment during admission to an intensive care or coronary care unit (ICU/CCU). Material/Methods: A retrospective cohort study including all the AMI patients treated with alteplase recorded in the ARIAM register (Analysis of Delay in AMI), a multi-center register in which 77 Spanish hospitals participate. The study period was from January 1995 to January 2000. Results: 4615 AMI patients were studied. THe accelerated regimen (Group I) was administerd to 57.51 p.c. (2,654 patients) and the remaining 42.49 p.c. (1,961 patients) received the double bolus regimen (Group II). There were no differences in mortality or in teh incidence of hemorhagic strokek between the groups. THe mortality was 7.15 p.c. in Group I versus 6.43 p.c. in Group II (not significant). The incidence of hemorrhagic stroke was 1.o9 p.c. in Group I versus 1.22 p.c. in Group II (not significant). Fewer coronary angiograpies were required in Group I (6.28 p.c. vs. 8.99 p.c.; p 0.001) and fewer rescue angioplasties (10.67 p.c. vs. 21.88 p.c., p = 0.03). Group I also showed a smaller requirement for stent insertion (1.45 p.c. vs e.77 p.c.; p 0.0001) and for assistance using intra-aortic balloon contrapulsation (0.47 p.c. vs. 1.36 p.c.; p = 0.02). Conclusions: The two regimens appear to be similar in efficacy and safety. Nevertheless, from these results it may be hypothesized that further revascularization techniques are required after double bolus administration.

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