Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL
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DIAZ-CASTELLANOS
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Tytuł oryginału:
Clinical implications of acute mycoardial infarction complicated by high grade atrioventricular block.
Autorzy:
Ruiz-Bailn
Manuel,
Hoyos
Eduardo Aguayo de,
Issa-Khozouz
Ziad,
Diaz-Castellanos
Miguel Angel,
López-Martinez
Asunción,
Calatrava-López
Jess,
Barranco-Ruiz
Mercedes,
Ruiz-Ferrón
Francisco,
Muńoz-Beltran
Humberto Jos
Źródło:
Med. Sci. Monitor 2002: 8 (3) s.CR138-CR147, tab., bibliogr. 35 poz.
Sygnatura GBL:
313,278
Hasła klasyfikacyjne GBL:
kardiologia
Typ dokumentu:
praca kliniczna
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
dorośli = 65 r.ż.
płeć męska
płeć żeńska
Streszczenie angielskie:
Background: The purpose of this study was to assess the incidence, clinical course, prognosis and mean length of stay in acute myocardial infarction (AMI) complicated by high-grade atrioventricular block (HAVB). Material/Methods: A retrospective cohort study including all AMI patietns listed from january 1995 to September 2000 in the ARIAM multi-center register. Univariate analysis was carried out to study the factors associated with the development of HAVB, the mortality ratek, and the mean length of stay, and multivariate logistic regression analysis to study whether HAVB is an independent predictive variable for mortality or prolongation of stay. Results: Of the 14.181 AMI patients included int he register, 837 (5.9 p.c.) presented with HAVB, which was associated with age, female sex, increased severity, diabetes, inferior and Q-wave AMIs, and a higher peak creatine phosphokinase (CPK) level. The HAVB patietns developed more complications, required more diagnostic-therapeutic resources, and showed significantly higher mortality (p 0.0001) and increased mean length of stay (p 0.0001). The independent risk factors for HAVB were age, maximum peak CPK, inferior or combined localization of the AMI, Q-wave AMI, diabetes, a Killip and Kimbal score 1, and thrombolysis. HAVB was found to be an independent predictive vairable for mortality and increased mean length of stay. Conclusions: AMI patients with HAVB, despite thrombolytic treatment, are at risk for complications, amortality and longer mean admissions. Further study is needed on the outcome of a more active reperfusion policy, such as direct, rescue angioplasty etc.
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Tytuł oryginału:
Alteplase: double bolus versus accelerated regimen.
Autorzy:
Ruiz-Bailen
Manuel,
Hoyos
Eduardo Aguayo de,
Hurtado-Ruiz
Benjamin,
Reina-Toral
Antonio,
Diaz-Castellanos
Miguel Angel,
Issa-Khozouz
Ziad
Źródło:
Med. Sci. Monitor 2002: 8 (10) s.PI85-PI92, il., tab., bibliogr. 30 poz.
Sygnatura GBL:
313,278
Hasła klasyfikacyjne GBL:
farmacja
kardiologia
Typ dokumentu:
praca kliniczna
tytuł obcojęzyczny
Wskaźnik treści:
ludzie
Streszczenie angielskie:
Background: The purpose of our study was to compare the efficacy and safety fo alteplase in acute myocardial infarction (AMI), when administered in a double bolus regimen or an accelerated regiment during admission to an intensive care or coronary care unit (ICU/CCU). Material/Methods: A retrospective cohort study including all the AMI patients treated with alteplase recorded in the ARIAM register (Analysis of Delay in AMI), a multi-center register in which 77 Spanish hospitals participate. The study period was from January 1995 to January 2000. Results: 4615 AMI patients were studied. THe accelerated regimen (Group I) was administerd to 57.51 p.c. (2,654 patients) and the remaining 42.49 p.c. (1,961 patients) received the double bolus regimen (Group II). There were no differences in mortality or in teh incidence of hemorhagic strokek between the groups. THe mortality was 7.15 p.c. in Group I versus 6.43 p.c. in Group II (not significant). The incidence of hemorrhagic stroke was 1.o9 p.c. in Group I versus 1.22 p.c. in Group II (not significant). Fewer coronary angiograpies were required in Group I (6.28 p.c. vs. 8.99 p.c.; p 0.001) and fewer rescue angioplasties (10.67 p.c. vs. 21.88 p.c., p = 0.03). Group I also showed a smaller requirement for stent insertion (1.45 p.c. vs e.77 p.c.; p 0.0001) and for assistance using intra-aortic balloon contrapulsation (0.47 p.c. vs. 1.36 p.c.; p = 0.02). Conclusions: The two regimens appear to be similar in efficacy and safety. Nevertheless, from these results it may be hypothesized that further revascularization techniques are required after double bolus administration.
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