Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: DEYAK
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Tytuł oryginału: Risk factors of sudden cardiac death in patients with unstable angina: results of a prospective 4-year follow-up trial.
Tytuł polski: Czynniki ryzyka nagłego zgonu sercowego u chorych z niestabilną chorobą wieńcową. Wyniki prospektywnej, 4-letniej obserwacji.
Autorzy: Malidze David, Sychov Oleg, Chubuchny Vladislaw, Deyak Sergey, Epanchintseva Olga
Źródło: Kardiol. Pol. 2002: 56 (1) s.20-30, il., tab., bibliogr. 23 poz. - 22 Kongres Europejskiego Towarzystwa Kardiologicznego Amsterdam 2000 - Tekst równoległy w jęz. pol.
Sygnatura GBL: 313,397

Hasła klasyfikacyjne GBL:
  • kardiologia

    Typ dokumentu:
  • praca kliniczna
  • praca związana ze zjazdem

    Wskaźnik treści:
  • ludzie
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background. Sudden cardiac death (SCD) is one of the most serious problem in modern cardiology. Risk factors of SCD in patietns who suffered from myocardial infarction (MI) have been accurately identified in large international trials. however, regarding patients with unstable angina (UA), data in literature are conflicting and not conclusive. Aim. TO estimate independent risk factor of SCD in patietns with UA during a 4 year follow-up. Methods. Three hundred ninety eight male patients with a mean age of 51.2 ń 8.0 years were prospectively evaluated after clinical stabilisation was achieved. Clinical data, echocardiography, 24-hour Holter ECG monitoring, transoesophageal pacing, bicycle ergometry and selective coronary angiography results were included in the multivariate analysis. Results. During a 4-year follow-up, SCD occurred in 44 (11.5 p.c.) patients. The final model for independent predictors of SCD revealed that the following variables were significantly related to SCD: age ň 60 years (OR = 1.74, 95 p.c. CI 0.91 - 3.82), nocturnal angina (OR = 2.20, 95 p.c. CI 1.37 - 5.67), heart failure in NYHA class II - III (OR = 2.10, 95 p.c. CI 1.14 - 4.490, more then (OR = 2.0 95 p.c. CI 1.05 - 4.13), more then 2 episodes of silent ischemia in a 24-hour Holter ECG monitoring (OR = 1.45, 95 p.c. CI 0.21 - 4.83), and ST-segment depression in ň 3 leads during bicycle ergometry (OR = 1.83, 95 p.c. CI 1.13 - 6.78). Conclusions. Our results confirm that risk factors associated with coronary artery disease and cardiac death are common in patients with UA. Assessment of independent risk factors on the basis of clinical characteristic and non-invasive tests may be useful for prediction of SCD in patietns with UA.

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