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Tytuł oryginału: Antigenic and allergenic properties of Amaranthus spinosus Pollen - a commonly growing weed in India.
Autorzy: Singh Anand B., Dahiya Pushpa
Źródło: Ann. Agric. Environ. Med. 2002: 9 (2) s.147-151, il., tab., bibliogr. 22 poz.
Sygnatura GBL: 313,158

Hasła klasyfikacyjne GBL:
  • immunologia

    Typ dokumentu:
  • praca kliniczna
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Amaranthus spinosus (Fam. Amaranthaceae) is an important aeroallergen in India and grows commonly in different parts of the country. In spite of its clinical significance in Type I hypersensitivity disorders, the antigenic and the allergenic properties of the epollen have not been systematically resolved. We investigated antigenic and allergenic properties of 5 pollen samples of Amaranthus spinosus collected from the Delhi area of fortinghtly intervals. The protein content did not exhibit statistically significant variability. However, samples collected during the peak flowering season showed higher protein content. Biochemical characterization of samples showed multiple protein fractions bay IEF and SDS-PAGE analysis. Samples collecated during peak sesason showed a slightly higher number of bands (22) in the mw range of 14-70 kD. Seven protein fractions of 70, 66, 60, 50, 40, 30 and 14 kD were observed to have IgE binding capabilities and 9 were treated as allergenic. The observations will be helpful in standardizing pollen antigens for diagnosis and immunotherapy in India.

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