Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: COSKUN
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Mast cell density, neuronal hypertrophy and nerve growth factor expression in patients with acute appendicitis.
Autorzy: Coskun Nigar, Sindel Muzaffer, Elpek Glsm ™zlem
Źródło: Folia Morphol. 2002: 61 (4) s.237-243, il., tab., bibliogr. 41 poz.
Sygnatura GBL: 301,720

Hasła klasyfikacyjne GBL:
  • gastroenterologia
  • neurologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: In acute appendicitis, although the relationship between the enteric nervous system (ENS) and mast cells (MCs) has been described in a few studies, neither the expression of nerve growth facor (NGF) nor its relation to mast cell density (MCD) and ENS has been delineated yet in this disease. The aim of this study was to immunohistochemically investigate the relationship between MCD, nervous system and NGF expression in the appendices of cases with clinically and histopathologically diagnosed acute appendicitis and of normal controls. Twenty-five patients with acute appendicitis and twelve normal controls were included in our study. Mast cell tryptase, PGP 9.5 and anti-NGF immunostained tissue sections were subjected to quantitative image analysis. Our results showed that MCD, the number of Schwann cells, the number and size of ganglia and NGF staining were significantly greater in acute appendicitis than in the control group (p 0.01). A strong correlation between MCD and NGF staining was detected (r = 0.92) only in cases with acute appendicitis. Similarly MCD was also related to neuronal proliferation and hypertrophy in this group. We failed to detect any relationship between NGF staining and neural components either in the acute appendicitis or control groups. Our findings indicate that mast cells could be one of the important cell populations responsible for nerve proliferation and hypertrophy in acute appendicitis. The relationship between NGF staining and MCD and the lack of correlation between NGF staining and changes in neural components suggest that, in acute appendicitis, NGF might be responsible for the increased number of MCs, but not for neuronal proliferation and hypertrophy.

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    Tytuł oryginału: Multiple muscular variations in the neck region - case study.
    Autorzy: Coskun Nigar, Yildirim Fatos Belgin, Ozkan Olcay
    Źródło: Folia Morphol. 2002: 61 (4) s.317-319, il., bibliogr. 10 poz.
    Sygnatura GBL: 301,720

    Typ dokumentu:
  • praca kliniczna
  • praca kazuistyczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska

    Streszczenie angielskie: During routine educational dissection studies, we encountered multiple muscular anomalies in a 25-year-old embalmed male cadaver. The muscular anomalies were observed on the right side. In accordance with theri origin, insertion and innervation features, the abormal muscles were considered sternocleidoccipital, sternomastoid and cleidomastoid muscles. The unilateral muscle variations were observed in both the superficial and deep layer. In the superficial layer, there were two muscles and one muscle bundle, while there was only one muscle in the deep layer. THe first muscle in the superficial layer, known as sternocleidooccipital muscle, consisted of clavicular head and sternal head. The second muscle in the superficial layer was sternomastoid muscle. The muscle observed in the deep layer was cleidomastoid muscle. Additionally, a muscular bundle was observed between the sternocleidoccipital and sternomastoid muscles. A combination of these variations in the same case has not, to our knowledge, been previously described in the available literature.

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