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Tytuł oryginału: 111 In-platelest dynamic study in chronic immune thrombocytopenic purpura.
Autorzy: Todorović-Tirnanić Mila V., Obradović Vladimir B., Pavlović Smiljana V., Suvajdzić Nada D., Elezović Ivo V., Colović Milica D., Bosnjaković Vladimir B.
Źródło: Nucl. Med. Rev. 2002: 5 (2) s.121-125, il., tab., bibliogr. 17 poz.
Sygnatura GBL: 313,603

Hasła klasyfikacyjne GBL:
  • pediatria
  • radiologia
  • hematologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dzieci 13-18 r.ż.
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: The aim of this work was to estimate the significance of a dynamic study performed during the first 20 minutes afetr autologous 111In-oxinate-platelets injection in patients with chronic immune thrombocytopenic purpura (ITP). Two hypotehses were tested: a) dynamic study indicates the place of platelet sequestration; b) dynamic study reflects the quality of platelet separation and labelling procedure. Material and methods: Thirty-nine persons were investigated: 25 with shortened platelet life span (ITP) and 14 with noraml platelet life span (6 healthy subjects and eight patients with myelodysplastic syndrome - MDS). Platelet blood count on the day of platelet labelling, general yield of platelet labelling (GYL), differential yield of platelet labelling (DYL), platelet life span, dynamic study with initial platelet accumulation in the liver (IPAL), sequential static study for determining the platelet sequestration index (SI) and platelet sequestartion site (SS) were investigated. Results: Two types of labelled platelet kinetics were determined in both groups of patients : OPAL 20 p.c. and IPAL 20 p.c. A statistically significant difefrence in GYL and DYL was noted between the patients with IPAL 20 p.c. and IPAL 20 p.c. No significant difefrence was registered in platelet blood count, life span, SS and SI bewteen the two groups of patients. Both yields of platelet labelling were higher in the group with IPAL 20 p.c. There was no correlation bewteen IPAL and platelest SI, or between ...

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