Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: CASTRO
Liczba odnalezionych rekordów: 4



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Tytuł oryginału: Unknown lung pathology in patients with cystic fibrosis is becoming known.
Autorzy: Kulczycki Lucas L., Castro Henry J., Castro Marcela Jimenez, Bellanti Joseph A.
Źródło: Ann. Diagn. Paediatr. Pathol. 2002: 6 (3/4) s.81-87, il., tab., bibliogr. 54 poz.
Sygnatura GBL: 313,395

Hasła klasyfikacyjne GBL:
  • gastroenterologia
  • pulmonologia

    Typ dokumentu:
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • płeć męska
  • płeć żeńska

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    Tytuł oryginału: Annals of Diagnostic Paediatric Pathology
    Tytuł angielski: Cushing's disease in a 5 months infant due to a basophilic microadenoma of the pituitary gland.
    Autorzy: Ferraz Maria Lucia da Fonseca, Oliveira Gamaniel de, Almeida Joao, Reis Marlene Antonia dos, Teixeira Vincente de Paula Antunes, Castro Eumenia Costa da Cunha
    Źródło: Ann. Diagn. Paediatr. Pathol. 2002: 6 (3/4) s.141-143, il., bibliogr. 29 poz.
    Sygnatura GBL: 313,395

    Hasła klasyfikacyjne GBL:
  • endokrynologia
  • onkologia

    Typ dokumentu:
  • praca kazuistyczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • niemowlęta

    Streszczenie angielskie: We report a five-month old girl with classical clinical features of Cushing's syndrome. Histological findings showed a basophilic microadenoma of the pituitary gland, leading to a diagnosis of Cushing disease (CD). The child died because of untreatable septic shock. The importance of the present report resides in the age of the child at the diagnosis. CD is the most often diagnosed in children older than seven years, and our patient was only five months old when we detected the pituitary adenoma, this was the earliest case diagnosed thus far. Cushing's syndrome in pediatric patients has been rarely reported and most of the cases are due to functioning adrenal tumour, usually a malignant carcinoma but occasionally a benign adenoma. The present case shows that the pituitary of this patients should be investigated with important implications in terms of therapeutic approaches such as radiotherapy of the pituitary, which can cure the patient when treatment is started as soon as possible.

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    Tytuł oryginału: Resistance mutations in HIV-infected patietns experiencing early failure with nelfinavir-containing triple combinations.
    Autorzy: Nuńez Marina, Mendozaut. Carmen de, Valer Luisa, Casas Esperanza, López-Calvo Soledad, Castro Angeles, Rosón Beatriz, Podzamczer Daniel, Rubio Amalia, Berenguer Juan, Soriano Vincent
    Źródło: Med. Sci. Monitor 2002: 8 (9) s.CR620-CR623, tab., bibliogr. 20 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • toksykologia
  • aIDS
  • genetyka

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.

    Streszczenie angielskie: Background: The purpose of our study was to assess the presence of nelfinavir (NFV)-associated resistance mutations at the time of early virological failure in subjects receiving NFV as part of a first protease inhibitor (PI)-based triple regimen. Material/Methods: Subjects failing their first PI-based NFV-containing triple regimen were identified in six Spanish hospitals. HIV genotyping was carried out in plasma samples collected at the time of the first viral rebound. Results: Upon initiation of NFV-based therapy, 19 of the 30 subjects (63 p.c.) werena‹ve; 11 (37 p.c.) had been exposed to nucleoside analogues. Median HIV-RNA at the time of viral rebound was 4, 180 copies/ml. PCR-amplified products were obtained in 22 subjects (73 p.c.). These products were sequenced and primary PI resistance mutations were recognized in 6 patietns (27 p.c.). All six individuals harbored the D30N mutation, and none presented the L90M mutation. Other PI resistance mutations were present in 5 subjects (at codons 36, 63, 71, 77, 82 and/or 88). Secondary PI resistance mutations were present in another 9 subjects. By contrast, mutations conferring resistance to reverse transcriptase nhibitiors were present in 50 p.c. of the patietns, and the M184V substitution was the most frequently seen. Conclusions: Nearly 75 p.c. of patietns failing their first PI-based triple regiment containing NFV do not harbor PI resistance mutations. THe D30N substitution, rather than L90M, is the msot frequently recognized, which does not challenge the efficacy of further rescue interventions with other PIs. This observation supports the use of nelfinavir as first protease inhibitor.

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    Tytuł oryginału: Role of surgery in pulmonary tuberculosis.
    Autorzy: Freixinet Jorge, Rivas Juan Jose, Castro Felipe Rodriquez de, Caminero Jose Antonio, Rodriquez Pedro, Serra Mireia, Torre Mercedes de La, Santana Norberto, Canalis Emilio
    Źródło: Med. Sci. Monitor 2002: 8 (12) s.CR782-CR786, tab., bibliogr. 30 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • chirurgia
  • pulmonologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: The purpose of our study was to analyze current indications for surgery in tuberculosis (TB). We present our experience with TB patients presenting with indications for surgery between 1990 and 1998. Material/Methods: The indications for surgical intervention included 25 cases of pulmonary aspergilloma, 19 cases of pneumothorax, 16 cases of pulmonary nodes and masses without histological diagnosis, 15 cases of bronchiectasis, 12 cases of massive hemoptysis, 12 cases of pleural empyema, and 33 cases of other complications. No patients with multidrug-resistant tuberculosis required surgical intervention, although 56 were treated during this period. Results: The techniques utilized included lobectomy in 45 cases, pleural drainage in 32 cases, segmented pulmonary resection in 32 cases, surgical procedures on the thoracic wall in 17 cases, pneumonectomy in 10 cases, pleuropulmonary decoration in 8 cases, medaistinoscopy in 6 cases, and thoracoscopy in 5 cases. In 25 cases two or more procedures were performed on the same patient. In 36 cases (27.3 p.c.) there were complications, of which persistent air leakage after pulmonary resection was the most frequent (n=10). There was a mortality rate of 5.3 p.c. (7 cases). Conclusions: In our experience, surgery in the treatment of TB is indicated to resolve sequelae or complications, since cases of simple or multidrug-resistant TB can be managed pharmacologically. The morbidity and mortality rates in our series were acceptable.

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