Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: BLIN
Liczba odnalezionych rekordów: 2



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Tytuł oryginału: Magnetic resonance imaging of arterial thrombi and its possible correlation to fibrinolytic treatment.
Autorzy: Kozak Matija, Blinc Ales, Sersa Igor, Mikac Ursa, Surlan Milos
Źródło: Cell. Mol. Biol. Lett. 2002: 7 (1) s.82-86, il., tab., bibliogr. 7 poz. - Międzynarodowa konferencja pt. Nauki przyrodnicze 2001 Gozd Martuljek 22-26.09. 2001
Sygnatura GBL: 306,513

Hasła klasyfikacyjne GBL:
  • kardiologia
  • radiologia

    Typ dokumentu:
  • praca kliniczna
  • praca związana ze zjazdem
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: For 13 patients with subacute and 4 patients with chronic occlusion, magnetic resonance imaging (MRI) of occlusive arterial thrombi in the superficial femoral artery were performed in vivo. The patients with subacute occlusion were treated with cetheter-directed thrombolysis. The frequency of MR signal intensity and its distribution in thrombi were studied for 11 successully adn 2 unsuccessfully treated patients and patients with chronic occlusion. Intra-araterial thrombi were MRI inhomogenous in all of the patients, abut the MR signals from lysable and chronic thrombi were significantly different than those from nonlysable ones. The MRI of occusive arterial thrombi is probably usaable to predict the therapeutic outcome of thrombolytic treatement.

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    Tytuł oryginału: Documenting ancient DNA quality via alpha satellite amplification and assessment of clone sequence diversity.
    Autorzy: Pusch Carsten M., Kayademir Tuncay, Prangenberg Kurt, Conrad Nicholas J., Czarnetzki Alfred, Blin Nikolaus
    Źródło: J. Appl. Genet. 2002: 43 (3) s.351-364, il., tab., bibliogr. s. 362-364
    Sygnatura GBL: 305,055

    Hasła klasyfikacyjne GBL:
  • genetyka

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • historia starożytności

    Streszczenie angielskie: C/G- T/A nucleotide alterations have been shown to hamper the straightforward interpretation of mitochondrial DNA sequence data derived from ancint tissues. Attempting to characterise this finding with respect to nuclear DNA, we contrasted two estabilished protocols: (i) an enzymatic reppair of damaged DNA, thereby translating and closing nicks in the DNA, and (ii) the application of N-phenacylthiazolium bromide, which cleaves glucose-derived protein crosslinks, presumably derived from Maillard reactions. We used medieval human bones that were refractory to standard PCR procedures. Due to negligible presence of short tandem repeat loci adn also mitochondrial sequences, the extracted ancient DNA needed a higher copy PCR system to yield amplification products. The chosen PCR target was specific alphoid repetitive DNA with an experimentally determined minimum of 1000 copies per haploidgenome. Alphoid repeat segments were generated from both contemporary DNA and dNA extracts of two human skeletons dating from 450-600 AD (omitting uracil N-glycocylase pre-treatment of the extracted samples), and were subsequently cloned and sequenced. The sequences were evaluated for the number type of nucleotide alternations noted after the different pre-treatments, and were compared to our alphoid consensuses sequence generated from modern DNA. Both methods failed to reflect the expected 32 p.c. variability among single alphoid repeats (accounting for locus-specific differences and polymerase errors) as well as to display the actual 2.88 ratio of ...

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