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Tytuł oryginału: Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.
Autorzy: Marszał Elżbieta, Wojaczyńska-Stanek Katarzyna, Pietruszewski Jerzy, Emich-Widera Ewa, Bielińska-Bujniewicz Eugenia
Źródło: Med. Sci. Monitor 2002: 8 (3) s.CR217-CR222, tab., bibliogr. 16 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • neurologia
  • pediatria

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • niemowlęta
  • dzieci 2-5 r.ż.
  • dzieci 6-12 r.ż.
  • dzieci 13-18 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with non-progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE). The study was designed to determine whether there is difference between the serum and CSF lactic acid concentrations in children with progressive encephalopathies (PE), static (non-progressive) encephalopathies (NPE) and non progressive encephalopathies with concomitant epilepsy (NPEE), and whether the clinical status correlates with the concentration of these biochemical markers in children with PE. Material/Methods: The assessment involved 138 children of both sexes, whose age ranged between 8 months and 15 years, diagnosed and treated in the Neurology Department at the Pediatric Clinica of the Silesian Medical Academy in Katowice between 1995 and 1997. Lactate concentrations were determined in serum and cerebro-spinal fluid and analyzed statistically. Results: The findings showed higher serum and CSF concentrations in children with PE than in patietns who manifested non-progressive forms of encephalopathy. The degree of clinical symptom aggravation in PE children was likewise analyzed an compared to the values of lactate concentrations in body fluids; however, no correlation was found between these parameters. Conclusion: Children with progressive encephalopathies present higher lactate concentrations in serum and cerebrospinal fluid than patients with static (non-progressive) encephalopathy.

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