Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Ocena akytywności elektrycznej przepony u chorych na POChP.
Tytuł angielski: Diaphragm electrical activation in COPD patients.
Autorzy: Bieleń Przemysław, Śliwiński Paweł
Źródło: Pneumonol. Alergol. Pol. 2002: 70 (7/8) s.378-386, il., tab., bibliogr. 12 poz., sum.
Sygnatura GBL: 301,096

Hasła klasyfikacyjne GBL:
  • pulmonologia

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • płeć męska

    Streszczenie angielskie: Several studies have demonstrated relatively moderate increase in Pdi during exhaustive exercise in COPD patients. The present study was designed to determine whether the small increase in Pdi is due to a central inhibition of respiratory drive, or an inability of the diaphargm to developpressure. Diaphragm electrical activation (Edi) and transdiaphragmatic (Pdi) pressure were measured in 19 patients with severe COPD using an esophageal catheter. End-expiratpry lung volume (EELV) was assessed by inspiratory capacity (IC) maneuvers. Maximal voluntary Edi (Edi max) was obtained during these maneuvers. EELV increased during exercise (p 0.001) causing end-inspiratory lung volume to attain 98 ń 5 p.c. of TLC at end-exercise. Pdi at rest was 8.4 ń 2.6 cm H2O. Edi was 19 ń 4 p.c. of Edi max at rest and increased progressively during exercise (p 0.001) to reach 78 ń 3 p.c. of Edi max at end-exercise. In conclusion, dynamic hyperinflation during exhaustive exercise in patients with COPD, reduces diaphragm pressure generating capacity, promoting near maximal levels of diaphragm activation without evidence of central inhibition.


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    Tytuł oryginału: Ocena czynności mięśni wydechowych u chorych na przewlekłą obturacyjną chorobę płuc.
    Tytuł angielski: Role of expiratory muscles in COPD patients.
    Autorzy: Bieleń Przemysław, Śliwiński Paweł
    Źródło: Pneumonol. Alergol. Pol. 2002: 70 (7/8) s.387-397, il., tab., bibliogr. 16 poz., sum.
    Sygnatura GBL: 301,096

    Hasła klasyfikacyjne GBL:
  • pulmonologia

    Typ dokumentu:
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • płeć męska

    Streszczenie angielskie: Expiratory muscle recruitment is common in stable COPD patients. However, physiological significance of expiratory muscle recruitment in COPD remains unclear. The purpose of this study was to assess the effect of expiratory muscle contraction on force generating ability of the diaphragm in COPD patients breathing at rest. The force generating ability of the diaphragm was evaluated from its pressure swing (Pdi) for a given diaphragm electrical activity (Edi), where Edi was normalized as p.c. of its maximal value [Pdi/(Edi)/Edi max)]. Phasic expiratory muscle contraction was measured as teh total rise in gastric pressure (Pga exp, rise). Nineteen patients with severe COPD, participated in the study but only 10 exhibited phasic rise in Pga during expiration with a mean Pga exp, rise of 1,91 ń 0,89 cmH2O. Patients were dividede into passive expiration (PE) and active expiration (AE) groups. There was no significant difference in lung function and breathing pattern parameters between the two groups. Pdi/(Edi/Edi max) was 0,63 ń 0,07 and 0,54 ń 0,07 cm cmH2O/p.c. in PE and AE groups, respectively, and was not significantly different between each other. Compared with PE group, AE group not only recruited expiratory muscles, but also preferentially recruited insiratory rib cage muscles and derecruited the diaphragm. In conclusion phasic contraction of expiratory muscles at rest in COPD patients do not improve the force-generating ability of the diaphragm.

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