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Tytuł oryginału: Urine microalbumin excretion in relation to exercise-induced electrocardiographic myocardial ischaemia.
Autorzy: Waldron Julian S., Baoku Yetunde, Hartland Andrew J., Anderson Neil R., Horton Richard C., Gama Rousseau
Źródło: Med. Sci. Monitor 2002: 8 (11) s.CR725-CR727, tab., bibliogr. 7 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • kardiologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.

    Streszczenie angielskie: Background: Microalbuminuria, a marker of endothelial cell dysfunction, is associated with atherosclerosis and is a predictor of coronary heart disease. It has been suggested that patients with coronary heart disease have exaggerated exercise-induced urinary microalbumin excretion but this is controversial. We, therefore, measured urine microalbumin excretion in men before and after an exercise electrocardiogram. Material/Methods: Urine microalbumin excretion expressed as the albumin-creatinine ratio (ACR) was measured before and after an exercise electrocardiogram in 10 subjects with exercise-induced myocardial ischaemia and 14 subjects without exercise-induced myocardial ischaemia. Results: In subjects with a positive exercise electrocardiogram, the pre-exercise electrocardiogram ACR 3.3 ń 5.50; (mean ń SD) significantly increased (p = 0.0371) follwoing exercise (6.30 ń 10.25). In subjects with a negative exercise electrocardiogram, the pre-exercise electrocardiogram ACR (0.73 ń 0.52) also significantly increased (p = 0.0295) following exercise (2.04 ń 1.81). Pre-exercise ACR was higher (p = 0.0164) in subjects with a positive exercise electrocardiogram (3.3 ń 5.50) than in those subjects with a negative exercise electrocardiogram (0.73 ń 0.52). Incremental and post-exercise ACR were not significantly different in those with normal and abnormal exercise electrocardiograms. Conclusion: Patients with exercise-induced myocardial ischaemia have pre-exercise urine microalbumin excretion. Exaggerated uring microalbumin excretion in resposne to exercise is not associated with exercise-induced myocardial ischaemia.

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