Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Course of viral hepatitis B and combined B and C hepatitis in children treated for neoplastic diseases.
Autorzy: Kołtan Sylwia, Wysocki Mariusz, Kołtan Andrzej, Świątkiewicz Violetta, Styczyński Jan, Dębski Robert, Balcar-Boroń Anna
Źródło: Med. Sci. Monitor 2002: 8 (4) s.CR274-CR279, il., tab., bibliogr. 36 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • pediatria
  • toksykologia
  • mikrobiologia
  • gastroenterologia
  • onkologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • niemowlęta
  • dzieci 2-5 r.ż.
  • dzieci 6-12 r.ż.
  • dzieci 13-18 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Background: Viral hepatitis C in children is milder than in adults. Patients with tumors, because of immune deficits, seem to be at risk of rapid liver disease progression. Little is known about the course of HCV and dual HBV-HCV infections in such patients. Material/Methods: The study assessed clinical courses of HCV and dual HBV-HCV infections in 249 children with tumors aged 1-18 years, divided into four groups: with HCV infection - 53, HBV-HCV infection - 53, HBV only - 33 and ifection-free - 110. Results: Hepatitis C was often chronic - in 83.3 p.c of patients with HCV and 77.3 p.c. of those with dual infection. Over 80 p.c. had no jaundice. Mean AIAT activity was the highest in the HCV group (149.2 ń 202.7 IU/l), lower in the dual infection group (123.3 ń 148.1 IU/l; p 0.02), and the lowest in HBV (92.7 152.9 IU/l. Transaminasemia course in patients with HCV and dual HBV-HCV infections was most frequently fluctuating (50.9 p.c. and 45.3 p.c., respectively). 52.8 p.c. of children with HCV demonstrated no advanced inflammatory lesions with invasion of the lamina limitans, no marked fibrosis, and minimum changes in descriptive classification. In 92.3 p.c. of children with dual infections, inflammatory activity was mild or mean, with no fibrosis in 61.5 p.c., and persistnet chronic inflammation predominant in descriptive classification (46.2 p.c.). Conclusions: HCV an HBV-HCV infections in children with neoplastic diseases tend to take chronic forms, but their clinical course is mild with signs of severeinflammatory activity or hepatitic strom aremodeling observed on histopathology.

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    Tytuł oryginału: Garr‚ type periostitis ossificans: effective antibiotic therapy case report and literature review.
    Autorzy: Styczyński Jan, Biliński Piotr, Lasek Władysław, Gajewska-Guryn Anna, Wysocki Mariusz, Balcar-Boroń Anna
    Źródło: Case Rep. Clin. Pract. Rev. 2002: 3 (1) s.46-50, il., bibliogr. 12 poz.
    Sygnatura GBL: 313,612

    Hasła klasyfikacyjne GBL:
  • pediatria
  • traumatologia i ortopedia

    Typ dokumentu:
  • praca kazuistyczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dzieci 6-12 r.ż.
  • płeć męska

    Streszczenie angielskie: Background: Garr‚ type periostitis ossificans is a rare disease observed in children and young adults. It is a chronic, infective pathologic change of bone tissue, with a mild course, affecting portions of long bone shafts and causing their sclerotization and thickening. Small granulation or cicatrization foci are present in teh marrow cavity, without purulence and bone defects. The predominant clinical symptom is dull pain, usually nocturnal. Generalized symptomsm or signs of local inflammation are rare. Case report: A course fo Garr‚ type periostitis ossificans located in the tibia of an 11-year-old boy is described. Laboratory tests and USG of the lesion site did not reveal any abnormalities. X-ray and CT images showed a spindle-shaped thickening of the tibial shaft, especially in the cortical layer, and narrowing of the marrow cavity, without periosteal reaction or soft tissue lesions. Scintigraphy of the skeletal system revealed enhanced radioligand uptake by the affected site. Differential diagnostics excluded osteogenci sarcoma, Ewing sarcoma, benign osteoma, cartilaginous tissue tumors, Langerhans cell histiocytosis and fibrous dysplasia. After antibiotic treatment, the clinical symptoms subsided. However, no evolution of radiological changes was observed. The boy has remained asymtomatic during 3-year follow-up. Conclusions: Garr‚ type periostitis ossificans should be taken into consideration in the differential diagnosis of bone diseases in children. The diagnosis is established on the basis of clinical and radiological presentation. Long-term antibiotic therapy may bring beneficial clinical effects. However, radiological changes of teh affected bone may persist for a long time.

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