Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Kontrol za efektivnihstju trivaloji antigihpertenzivnoji terapihji enalaprilom v praktichnihjj robotih sihmejjnogo lihkarja.
Tytuł angielski: Checking the effcacy of prolonged antihypertention therapy with enalapril in practical woru of a family doctor.
Autorzy: Nejjko Je. M., Orinchak M. A., Seredjuk N. M., Gorban Je. M., Vakaljuk Ih. P., Aleksandruk D. P., Jacishin R. Ih., Vihrstjuk N. G., Seredjuk V. N., Glushko N. L., Artemenko N. R., Lihbrik O. Ja., Cherkashina O. Je.
Źródło: New Med. 2002: 5 (1) s.13-15, bibliogr. 6 poz., sum.
Sygnatura GBL: 313,682

Hasła klasyfikacyjne GBL:
  • kardiologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: 137 patients in the middle and older age with arterial hypertension (AH) of the P and Sh stage were observed. The speading of AH in different regions of Precarpathia in dependance from climatical - geografical and socioeconomical conditions was studied. It was stated that the indexes of the daily monitoring of blood preassure are informational prognostical criterial of AH running and also are the criteria of the effectivness of the antihypertensive therapy. The effectiveness of the long time use of the angiotensin-converting enzyme inhibitor of enalapri in different age groups of the patients was proved. The study of psychological condition of the patient with the help to the questioneer may serve as the criteria of valuing the effectiveness of healing and social rehabilitation of the AH patients. The recommendation for the family doctors concerning healing and the prevention of the complicates of the AH on the base of the researth results were worked out.

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    Tytuł oryginału: The analysis of structure - anticancer and antiviral activity relationships for macrocyclic pyridinophanes and their analogues on the basis of 4D QSAR models (simplex representation of molecular structure).
    Autorzy: Kuz'min Victor E., Artemenko Anatoly G., Lozitsky Victor P., Muratov Eugene N., Fedtchouk Alla S., Dyachenko Natalia S., Nosach Lidiya N., Gridina Tatiyana L., Shitikova Larisa I., Mudrik Liubov M., Mescheriakov Aleksey K., Chelombitko Vladislav A., Zheltvay Andrey I., Eynde Jean-Jaques Vanden
    Źródło: Acta Bioch. Pol. 2002: 49 (1) s.157-168, il., tab., bibliogr. 19 poz. - 8 Międzynarodowe Sympozjum pt. Aspekty molekularne chemioterapii Gdańsk 09. 2001
    Sygnatura GBL: 303,116

    Hasła klasyfikacyjne GBL:
  • onkologia
  • mikrobiologia
  • farmacja

    Typ dokumentu:
  • praca związana ze zjazdem
  • praca przeglądowa
  • tytuł obcojęzyczny

    Streszczenie angielskie: A new 4D-QSAR approach has been considered. For all investigated moleucles the 3D structural models have been created and the set of conformers (fourth dimension) have been used. Each conformer is represented as a system of different simplexes (tetratomic fragments of fixed structure, chirality and symmetry). The investigation of influence of molecular structure of macrocyclic pyridinophanes, their analgues and certain other compounds on anticancer and antiviral (anti-influenza, antiherpes and antiadenovirus) activity has been carried out by means of the 4D-QSAR. Statistic charactierstics from QSAR of PLS (partial least squares) models are satisfactory (R = 0.94 - 0.97; CVR = 0.63 - 0.83).

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