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Tytuł oryginału: Skin rubdown with a dry towel activates natural killer cells in bedridden old patients.
Autorzy: Iwama Hiroshi, Akama Yoichi
Źródło: Med. Sci. Monitor 2002: 8 (9) s.CR611-CR615, il., tab., bibligor. 21 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • immunologia

    Typ dokumentu:
  • tytuł obcojęzyczny
  • praca kliniczna

    Wskaźnik treści:
  • ludzie
  • dorośli = 65 r.ż.

    Streszczenie angielskie: Background: Skin rubdown using a dry towel to scrub the whole body is a traditional procedure. Because massage therapy is effective in improving cellular immunity, skin rubdown may also have the similar effects. Material/methods: Sixteen bedridden old patients, who had suffered a cerebral stroke, were studied. Skin rubdown for about 10 minutes was added for 10 days. Blood was collected at noon on the day before skin rubdonw, 5 and 10 days after initiation and 5 days after completion, and the neutrophil count, lymphocyte count, serum gamma-globulin and C-reactive protein (CRP) levels and natural killer cell activity were measured. In 9 of these 16 patients, B, T, CD4 and CD8 lymphocyte counts were additionally measured on the same days. Reslults: There were no significant changes in teh time course of the lymphocyte count, gamma-globulin or CRP levels. The neutrophil count increased 10 days after initiation of the skin rubdown, and natural killer cell activity increased 5 and 10 days after initiation, and returned to the baseline level 5 days after completion. Although there were no changes in the time course of the B, T, CD4 and CD8 lymphocyte counts, the CD4/CD8 ratio showed an increase 5 days after initiation and completion. Conclusions: Skin rubdonw activates natural killer cells, which may be attributed to the effect of certain mediators released from teh T lymphocytes and/or the stimulated effect on the sympathetic nerves. The technique may be used to reduce a variety of complications caused by the decreased immunity observed in bedridden old patients.

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