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Tytuł oryginału: Wsakazania do leczenia immunosupresyjnego w dermatologii.
Tytuł angielski: Clinical applications of new immunosuppressive drugs.
Autorzy: Warmińska Julia, Kowal Anna, Krasowska Dorota
Źródło: Nowa Med. 2002: 9 (3) s.2-6, bibliogr. 34 poz., sum.
Sygnatura GBL: 313,229

Hasła klasyfikacyjne GBL:
  • immunologia
  • choroby zakaźne

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Immunosuppression consists in breaking of different immune reactions. According to mechanism of activity, these drugs reveal effects on each stage of the immune process. Among immunosuprressive drugs steroids, antimetabolites, alkylating agents, cyclosporine, mycophenolate mofetil are used in dermatology. Therapeutic potencial of these drugs is limited by dangerous side effects. Apart from inhibition the excessive immunological response to antigens and because of the lack of specific action, they results in total suppression of the immune system. That in turn produces higher number of infections, the abnormal course of diseases and increased risk of lymphomas and cancers. Therefore the decision on applying any of these immunosuppressive drugs ought to be preceded by thorough analysis of clinical history, indications and contraindications refering to each drugs and potencial toxicity and side effects.

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