Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: Autoaggregation, hydrophobic, and hydrophylic properties of Moraxella catarrhalis strains.
Autorzy: Janicka Grażyna, Mikucka Agnieszka, Sękowska Alicja, Zwierzchlewski Tomasz, Wróblewski Marcin
Źródło: Acta Microbiol. Pol. 2002: 51 (1) s.23-30, il., bibliogr. [27] poz.
Sygnatura GBL: 302,697

Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • pulmonologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • in vitro

    Streszczenie angielskie: The hydrophobicity of the bacterial cell surface was evaluated via the salt aggregation test (SAT) in 58 strains (19 from the lower and 39 from the upper respiratory tracts) of Moraxella catarrhalis in hospitalized patients aged 25 to 65. Based on the SAT results, the strains were divided into three groups: autoaggregating (highly hydrophobic), hydrophobic, and hydrophilic. At a temperature of 37řC, the autoaggregating, hydrophobic or hydrophilic properties did not depend on the choice of a medium, whereas at 22řC the investigated properties did (p 0.0001). Taking into account the origin of the strains (lower vs. upper respiratory tract), it was found that: in the strains cultivated in liquid medium, both highly hydrophobic, hydrophobic and hydrophilic surfaces were present with a comparative frequency, independent of the strain isolated site and cultivation conditions; strains with highly hydrophobic and hydrophobic surfaces, but only those cultivated on solid media at 22řC, were much more often isolated from sputum rather than from nose and throat swabs, whereas a ststistically significant incidence of hydrophilic strains was found in samples from the uppeer rather than lower respiratory tract.

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    Tytuł oryginału: Resistance of Klebsiella pneumoniae strains producing and not producing ESBL (extended-spectrum beta-lactamase) type enzymes to selected non-beta-lactam antibiotics.
    Autorzy: Sękowska Alicja, Janicka Grażyna, Kłyszejko Czesław, Wojda Małgorzata, Wróblewski Marcin, Szymankiewicz Maria
    Źródło: Med. Sci. Monitor 2002: 8 (3) s.BR100-BR104, il., tab., bibliogr. 33 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • mikrobiologia
  • farmacja

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: Background: Bacteria of the Klebsiella genus may cause numerous infections in human, which are often treatead with beta-lactam antibiotics. The fundamental mechanism of Klebsiella resistance to penicillns or cephalosporins involves the production of enzymes - extended-spectrum beta-lactamases (ESBLs). Because of resistance of many Klebsiella spp. strains to beta-lactams, alternative antibiotic therapy can make use of aminoglycosides and quinolones. Material/Methods: The study analyzed the prevalence of ESBL - type enzymes among 256 Klebsiella pneumoniae strains isolated from various clinical materials collected from patients hospitalized between 1997 and 2000. ESBLs were detected by double-disk synergy test (DDST). The prevalence of strains resistant to selected aminoglycosides (gentamicin, amikacin, netilmicin) and quidolones (ciprofloxacin, norfloxacin, nalidixic acid) in the particular years was analysed. Drug sensitivity was determined by disk-diffusion method according to the recommendations of the National Reference Center for Microbial Drug Sensitivity. Results: During the analyzed time interval, a significant increase of the number of K. pneumoniae ESBL(+) strains was noted: in 1997 - 16.5 p.c. (14/85) and in 2000 - 40.4 p.c. (22/54) (p 0.001). Among the ESBL (+) strains, an increase of the number of starins resistant to the tested antibiotics, excepto for anlidixic acid, was demonstrated. Conclusion: A statistically significant increase of multidrug-resistant K. pneumoniae strains, including strains producing ESBLs, was demosntrated in the analyzed material.

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