Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL
Zapytanie:
MACFARLANE
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Tytuł oryginału:
Age-adjustment of HRV measures and its prognostic value for risk assessment in patients late after myocardial infarction.
Autorzy:
Sosnowski
Maciej,
MacFarlane
Peter W.,
Czyż
Zbigniew,
Skrzypek-Wańha
Janina,
Boczkowska-Gaik
Ewa,
Tendera
Michał
Źródło:
Int. J. Cardiol. 2002: 86 (2/3) s.249-258, il., tab., bibliogr. 19 poz.
Sygnatura GBL:
305,693
Hasła klasyfikacyjne GBL:
kardiologia
Typ dokumentu:
praca opublikowana za granicą
tytuł obcojęzyczny
praca kliniczna
Wskaźnik treści:
ludzie
dorośli 45-64 r.ż.
dorośli = 65 r.ż.
płeć męska
płeć żeńska
Streszczenie angielskie:
The aims of our study were: (1) to establish the normal limit of the heart rate variability (HRV) indices in a healthy population and in its fourage-related subgroups, including a new HRV index, HRV fraction; and (2) to analyse the frequency and predictive value of abnormally low HRV in a population of post-infarction patients in respect to the cut-points chosen (raw or age-adjusted). Methods: Normal population of 296 healthy subjects (81 f, 215 m, aged 47 ń 10 years) and post-infarction population of 298 patients ( 3 months after acute MI, 65 f, 233 m, aged 56 ń 10) were examined. The normal population was divided into 4 subsets based on age at entry: 35, 35-44, 45-54 and 54 years. Based on a 24 h ECG the standard HRV analysis was performed to obtain the following indices: mean RR interval, SDNN and SDANN. A new index of HRV, HRV fraction (HRVF, p.c.) was calculated based on a numercial processing of the RR intervals return map. All patients were followed for 24 months. The endpoints of the study were death (of any reason) and cardiac death. Results: Means and normal limits for SDNN, SDANN and HRVF were: 147 ń 36 ms [95 p.c. CI 89-220], 136 ń 36 ms [79-212] and 53 ń 9 p.c. [35-68]. The HRV values below the lower normal limit (LNL) were observed in 20-25 p.c. of post-MI patients. During a 2 year follow-up there were 36 deaths (total mortality 12.1 p.c.), while cardiac mortality was 9.1 p.c. (27 cases). The prognostic value of the analysed indices was similar (sens 53-61 p.c., spec 79-84 p.c., PPV 2-26 p.c., NPV 93-94 p.c.)...
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